PF-1355 BOC Sciences

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Supplier Name	BOC Sciences
Contact	Linna Green
Tel	+16314854226
Mobile	+16314854226
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Email	info@bocsci.com
Website	https://www.bocsci.com/
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LinkedIn	https://www.linkedin.com/company/boc-sciences

Product Name	PF-06281355
Synonyms	PF1355 PF-1355 PF 1355 PF06281355 PF 06281355 PF-06281355 PF-06281355 (Free base) Synonyms PF1355 PF-1355 PF 1355 PF06281355 PF 06281355 PF-06281355 PF-06281355 (Free base) 6-(2,5-Dimethoxyphenyl)-3,4-dihydro-4-oxo-2-thioxo-1(2H)-pyrimidineacetamide 1(2H)-Pyrimidineacetamide, 6-(2,5-dimethoxyphenyl)-3,4-dihydro-4-oxo-2-thioxo- 2-(6-(2,5-dimethoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide
CAS	1435467-38-1
EINECS
Chemical Formula	C14H15N3O4S
Molecular Weight	321.35
inchi
Package	50 mg
Price	$299
Descriptions	PF-1355 PF-1355 is a selective, mechanism-based inhibitor of myeloperoxidase (MPO) (IC50 = 1.5 μM in LPS-stimulated human whole blood) with excellent selectivity for MPO without disrupting a panel of 50 receptors, enzymes, ion channels and transporters, including thyroid peroxidase. PF-1355 was used to test the hypothesis that MPO activity is a critical mediator of disease activity in immune complex vasculitis mouse models, and to support the confidence in rationale for this mechanism as a therapeutic approach to treat related human condition such as alleviating tissue injury caused by Goodpasture syndrome and pulmonary vasculitis induced by immune complexes.
Supplier Website	https://www.bocsci.com/pf-1355-cas-1435467-38-1-item-474818.html
Last Update	2025-04-30 11:27:47

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