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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product NameBenzeneacetamide, 3,4-dichloro-N-[4-[[(5-methyl-3-isoxazolyl)amino]sulfonyl]phenyl]-
SynonymsWAY-616763;Benzeneacetamide, 3,4-dichloro-N-[4-[[(5-methyl-3-isoxazolyl)amino]sulfonyl]phenyl]-
CAS735303-62-5
EINECS
Chemical FormulaC18H15Cl2N3O4S
Molecular Weight440.3
inchi
PackageInquiry
PriceGet quote
DescriptionsPFK-IN-1

PFK-IN-1

MedChemExpress (MCE)

HY-128268

735303-62-5

Please store the product under the recommended conditions in the Certificate of Analysis.

Room temperature in continental US

Descriptions

PFK-IN-1

PFK-IN-1

MedChemExpress (MCE)

HY-128268

735303-62-5

Please store the product under the recommended conditions in the Certificate of Analysis.

Room temperature in continental US
may vary elsewhere.

PFK-IN-1 (compound 1) is a phosphofructokinase (PFK) inhibitor, with IC50 values of 0.41 and 0.23 μM against T.brucei and T.cruzi PFK, respectively, and an ED50 of 15.18 μg/mL for T.brucei. The half-lives of PFK-IN-1 in rat and mouse liver microsomes are 9.7 and 408 minutes, respectively.

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[1]. Kyle R Brimacombe, et al. Identification of ML251, a Potent Inhibitor of T. brucei and T. cruzi Phosphofructokinase. ACS Med Chem Lett. 2013 Oct 30
5(1):12-7. [Content Brief]

Supplier Websitehttps://www.medchemexpress.com/pfk-in-1.html
Last Update2025-05-21 16:50:25
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