Zolmitriptan-d6 MedChemExpress (MCE)

Product Name	Zolmitriptan-D6 (Major)
Synonyms	ZOLMITRIPTAN-D6;Zolmitriptan-D6 (Major);Zolmitriptan-D6 hydrochloride;(5R)-5-[[3-[2-[bis(trideuteriomethyl)amino]ethyl]-1H-indol-5-yl]methyl]-1,3-oxazolidin-2-one
CAS	1217644-84-2
EINECS
Chemical Formula	C16H15D6N3O2
Molecular Weight	293.39
inchi
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Descriptions	Zolmitriptan-d6 Zolmitriptan-d6 MedChemExpress (MCE) HY-B0229S 1217644-84-2 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions Zolmitriptan-d6 Zolmitriptan-d6 MedChemExpress (MCE) HY-B0229S 1217644-84-2 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Zolmitriptan-d6 is deuterium labeled Zolmitriptan. Zolmitriptan (BW-311C90 311C90) is a 5-HT1B/1D receptor partial agonist with Kis of 5.01 nM, 0.63 nM, and 63.09 nM for 5-HT1B, 5-HT1D, 5-HT1F receptor, respectively. Zolmitriptan can be used for the research of migraine[1][2]. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. \| \| \| \| \| \| \| \| \| \| [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 53(2):211-216. [Content Brief] [2]. G R Martin, et al. Receptor specificity and trigemino-vascular inhibitory actions of a novel 5-HT1B/1D receptor partial agonist, 311C90 (zolmitriptan). Br J Pharmacol. 1997 May 121(2):157-64. [Content Brief] [3]. Katherine C Murray, et al. Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors. J Neurophysiol. 2011 Aug 106(2):925-43. [Content Brief]
Supplier Website	https://www.medchemexpress.com/zolmitriptan-d6.html
Last Update	2025-05-21 16:50:25

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