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Supplier NameMedChemExpress (MCE)
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Product Name[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate
SynonymsGpppA
Guanosine triphosphate adenosine
guanosine 5'-triphosphate-5'-adenosine
[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate
CAS10527-47-6
EINECS
Chemical FormulaC20H27N10O17P3
Molecular Weight
inchi
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PriceGet quote
DescriptionsGuanosine 5'-triphosphate-5'-adenosine

Guanosine 5'-triphosphate-5'-adenosine

MedChemExpress (MCE)

HY-139101

10527-47-6

GpppA

Please store the product under the recommended conditions in the Certificate of Analysis.

Room temperature in continental US

Descriptions

Guanosine 5'-triphosphate-5'-adenosine

Guanosine 5'-triphosphate-5'-adenosine

MedChemExpress (MCE)

HY-139101

10527-47-6

GpppA

Please store the product under the recommended conditions in the Certificate of Analysis.

Room temperature in continental US
may vary elsewhere.

Guanosine 5'-triphosphate-5'-adenosine (GpppA), a 5′ cap analog, can be used for RNA synthesis in vitro. Guanosine 5'-triphosphate-5'-adenosine is a fluorescent substrate analog.

Guanosine 5'-triphosphate-5'-adenosine (GpppA) labeled with pyrene at the 3′‐O position of adenosine acts as an artificial substrate. Fluorescently labeled Guanosine 5'-triphosphate-5'-adenosine (GpppA) and GpppG analogs as potential substrates that represent a reasonable compromise between the structural complexity and requirements of the enzyme[1].

Human Endogenous Metabolite

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[1]. Renata Kasprzyk, et al. Direct High-Throughput Screening Assay for mRNA Cap Guanine-N7 Methyltransferase Activity. Chemistry. 2020 Sep 1
26(49):11266-11275.
[Content Brief]

[2]. Dennis Reichert, et al. Light-control of cap methylation and mRNA translation via genetic code expansion of Ecm1. Chem Sci. 2021 Feb 8
12(12):4383-4388.
[Content Brief]

Supplier Websitehttps://www.medchemexpress.com/guanosine-5-triphosphate-5-adenosine.html
Last Update2025-04-01 14:45:47
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