Aminocandin MedChemExpress (MCE)

Product Name	L-Proline, 4-[(2-aminoethyl)amino]-N2-[[4'-(octyloxy)[1,1'-biphenyl]-4-yl]carbonyl]-L-ornithyl-L-threonyl-(4R)-4-hydroxy-L-prolyl-4-(4-hydroxyphenyl)-L-threonyl-L-seryl-3-hydroxy-4-methyl-, (6→15)-lactam, (3S,4S)-
Synonyms	L-Proline, 4-[(2-aminoethyl)amino]-N2-[[4'-(octyloxy)[1,1'-biphenyl]-4-yl]carbonyl]-L-ornithyl-L-threonyl-(4R)-4-hydroxy-L-prolyl-4-(4-hydroxyphenyl)-L-threonyl-L-seryl-3-hydroxy-4-methyl-, (6→15)-lactam, (3S,4S)- Synonyms L-Proline, 4-[(2-aminoethyl)amino]-N2-[[4'-(octyloxy)[1,1'-biphenyl]-4-yl]carbonyl]-L-ornithyl-L-threonyl-(4R)-4-hydroxy-L-prolyl-4-(4-hydroxyphenyl)-L-threonyl-L-seryl-3-hydroxy-4-methyl-, (6→15)-lactam, (3S,4S)- Aminocandin
CAS	227472-48-2
EINECS
Chemical Formula	C56H79N9O14
Molecular Weight
inchi
Package	Inquiry
Price	Get quote
Descriptions	Aminocandin Aminocandin MedChemExpress (MCE) HY-P0068 227472-48-2 HMR 3270 Descriptions Aminocandin Aminocandin MedChemExpress (MCE) HY-P0068 227472-48-2 HMR 3270 IP960 NXL201 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Aminocandin (HMR 3270) is water-soluble antifungal agent of the echinocandin class with excellent activity against Aspergillus and Candida spp.. Aminocandin (HMR 3270) inhibits Fluconazole (HY-B0101)-resistant C. albicans strain MRL 648 with an MIC of 0.25 mg/L[2]. Aminocandin shows half-life of 48-58 h[2]. Aminocandin (1-10 mg/kg i.v. or i.p. once daily for 11 days) is highly effective in reducing mortality and organ burden in disseminated infection caused by ITC-susceptible and -resistant A. fumigatus in mice[1]. Aminocandin (5 and 10 mg/kg i.v. once or twice a week for 4 weeks) is an effective addition to the arsenal of antifungal compounds for the treatment of candidiasis caused by Fluconazole (HY-B0101)-resistant C. albicans in immunocompetent mice[2]. Fungal[1] In Vitro Aminocandin (HMR 3270) inhibits Fluconazole (HY-B0101)-resistant C. albicans strain MRL 648 with an MIC of 0.25 mg/L[2]. Aminocandin shows half-life of 48-58 h[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Aminocandin Related Antibodies \| \| \| \| \| \| \| \| \| \| [1]. Warn PA, et al. Activity of aminocandin (IP960 HMR3270) compared with amphotericin B, itraconazole, caspofungin and micafungin in neutropenic murine models of disseminated infection caused by itraconazole-susceptible and -resistant strains of Aspergillus fumigatus. Int J Antimicrob Agents. 2010 Feb 35(2):146-51. [Content Brief] [2]. Ghannoum MA, et al. Efficacy of aminocandin in the treatment of immunocompetent mice with haematogenously disseminated fluconazole-resistant candidiasis. J Antimicrob Chemother. 2007 Mar 59(3):556-9. [Content Brief]
Supplier Website	https://www.medchemexpress.com/aminocandin.html
Last Update	2025-05-21 16:50:25

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