β-Amyloid (1-17) MedChemExpress (MCE)

Product Name	β-Amyloid (1-17)
Synonyms	β-Amyloid 1-17 β-Amyloid (1-17) L-Leucine, L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-α-aspartyl-L-serylglycyl-L-tyrosyl-L-α-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-
CAS	186319-72-2
EINECS
Chemical Formula	C90H130N28O29
Molecular Weight	2068.2
inchi
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Descriptions	β-Amyloid (1-17) β-Amyloid (1-17) MedChemExpress (MCE) HY-P1772 186319-72-2 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions β-Amyloid (1-17) β-Amyloid (1-17) MedChemExpress (MCE) HY-P1772 186319-72-2 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. β-Amyloid (1-17) is a peptide of β-Amyloid, stabilizes the fibres and plays a role in Aβ fibre formation. β-Amyloid Aggregation Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs). 1. Solid Aβ peptide was dissolved in cold hexafluoro-2-propanol (HFIP). The peptide was incubated at room temperature for at least 1h to establish monomerization and randomization of structure. 2. The HFIP was removed by evaporation, and the resulting peptide was stored as a film at -20 or -80 ℃. 3. The resulting film was dissolved in anhydrous DMSO at 5 mM and then diluted into the appropriate concentration and buffer (serum- and phenol red-free culture medium) with vortexing. 4. Next, the solution was age 48h at 4-8 ℃. The sample was then centrifuged at 14000g for 10 min at 4-8 ℃ the soluble oligomers were in the supernatant. The supernatant was diluted 10-200-fold for experiments. Methods vary depends on the downstream applications. Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu \| \| \| \| \| \| \| \| \| \| [1]. Shi JM, et al. Dissecting the behaviour of β-amyloid peptide variants during oligomerization and fibrillation. Pept Sci. 2017 Nov 23(11):810-817. [Content Brief] [2]. Wei-wei Zhou, et al. Decreasing oxidative stress and neuroinflammation with a multifunctional peptide rescues memory deficits in mice with Alzheimer disease. Free Radic Biol Med. 2014 Sep 74:50-63. [Content Brief]
Supplier Website	https://www.medchemexpress.com/beta-amyloid-1-17.html
Last Update	2025-05-21 16:50:25

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