Zolmitriptan MedChemExpress (MCE)

Product Name	Zolmitriptan
Synonyms	139264-17-8 Zolmitriptan (S)-4-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl-2-oxazolidinone (4r)-4-[[3-(2-dimethylaminoethyl)-1h-indol-5-yl]methyl]oxazolidin-2-one 4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one Synonyms 139264-17-8 Zolmitriptan (S)-4-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl-2-oxazolidinone (4r)-4-[[3-(2-dimethylaminoethyl)-1h-indol-5-yl]methyl]oxazolidin-2-one 4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one (4R)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one (4S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one
CAS	139264-17-8
EINECS
Chemical Formula	C16H21N3O2
Molecular Weight
inchi	InChI=1/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m1/s1
Package	10 mM * 1 mL;50 mg;100 mg;500 mg
Price	Get quote
Descriptions	Zolmitriptan Zolmitriptan MedChemExpress (MCE) HY-B0229 139264-17-8 BW-311C90 Descriptions Zolmitriptan Zolmitriptan MedChemExpress (MCE) HY-B0229 139264-17-8 BW-311C90 311C90 99.98% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. Zolmitriptan (BW-311C90 311C90) is a 5-HT1B/1D receptor partial agonist with Kis of 5.01 nM, 0.63 nM, and 63.09 nM for 5-HT1B, 5-HT1D, 5-HT1F receptor, respectively. Zolmitriptan can be used for the research of migraine. Zolmitriptan (311C90) exhibits higher affinity to 5-HT than sumatriptan (pKA=6.63±0.04 and 6.16±0.03, respectively). 311C90 displays high affinity at human recombinant 5-HT1D and 5-HT1B receptors in transfected CHO-K1 cell membranes (pIC50 values=9.16±0.12 and 8.32±0.09, respectively) [1]. "Zolmitriptan (311C90 3-30 μg/kg, i.v.) causes a dose-dependent inhibition of [125I]-albumin extravasation within the ipsilateral dura mater. Zolmitriptan also produces dose-dependent falls in cranial vascular conductance (32.3% at 30 μg/kg)[1].Zolmitriptan is an anti-migraine agent with action at 5-HT1B/D receptors. Zolmitriptan is an effective and behaviorally specific anti-aggressive agent in situations that engender moderate and alcohol-heightened levels of aggression. Zolmitriptan (1-30 mg/kg, i.p.) exerts behaviorally specific anti-aggressive effects in mice[3]." 5-HT1B Receptor 5.01 nM (Ki) 5-HT1D Receptor 0.63 nM (Ki) 5-HT1F Receptor 63.09 nM (Ki) \| \| \| \| \| \| \| \| \| \| [1]. G R Martin, et al. Receptor specificity and trigemino-vascular inhibitory actions of a novel 5-HT1B/1D receptor partial agonist, 311C90 (zolmitriptan). Br J Pharmacol. 1997 May 121(2):157-64. [Content Brief] [2]. Katherine C Murray, et al. Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors. J Neurophysiol. 2011 Aug 106(2):925-43. [Content Brief]
Supplier Website	https://www.medchemexpress.com/Zolmitriptan.html
Last Update	2025-05-21 16:50:25

MedChemExpress (MCE) also provides

Glycyl-L-glutamine

Category: Natural Products
CAS: 13115-71-4
Last Update: 2025-05-21 16:50:25

Triose phosphate

Category: Natural Products
CAS: 591-57-1
Last Update: 2025-05-21 16:50:25

Lactyl-CoA

Category: Natural Products
CAS: 1926-57-4
Last Update: 2025-05-21 16:50:25

12(S)-HPETE

Category: Natural Products
CAS: 71774-10-2
Last Update: 2025-05-21 16:50:25

Pyrithiamine

Category: Natural Products
CAS: 534-64-5
Last Update: 2025-05-21 16:50:25

alpha-CEHC

Category: Natural Products
CAS: 4072-32-6
Last Update: 2025-05-21 16:50:25

Maltoheptaose

Category: Natural Products
CAS: 34620-78-5
Last Update: 2025-05-21 16:50:25

Phenoxyethanol

Category: Natural Products
CAS: 122-99-6
Last Update: 2025-05-21 16:50:25


Supplier Name	MedChemExpress (MCE)
Contact	sales
Tel	609-228-6898
Mobile	609-228-6898
QQ
Email	sales@medchemexpress.com; tech@medchemexpress.com
Website	https://www.medchemexpress.com/
Wechat

Request for quotation

Supplier Contact