Curcumin monoglucosideCurcumin monoglucoside
MedChemExpress (MCE)
HY-N12669
387818-26-0
Please store the product under the recommended conditions in the Certificate of Analysis.
Room temperature in continental US
may vary elsewhere.
Curcumin monoglucoside is a flavonoid derivative possessing antioxidant, anti-apoptotic, neuroprotective effects, and antibacterial activity. Curcumin monoglucoside can be used in research on Parkinson's disease.
Curcumin monoglucoside (5µM
24 h) exhibits anti-apoptotic effects in N27 cells by inhibiting the activation of caspase 3 through the prevention of JNK and c-jun phosphorylation[1]. Curcumin monoglucoside (0.25-5µM
24 h) significantly protects N27 cells from ROT (500 nM
24 h)-induced neuronal death, demonstrating neuroprotective effects[1].Curcumin monoglucoside exhibits antibacterial activity, with MIC (Minimum Inhibitory Concentration) values of 5, 5, and 10 μg/mL respectively against penicillin-sensitive, penicillin-intermediate, and penicillin-resistant strains of Streptococcus pneumoniae[2].
Curcumin monoglucoside (500µM) exerts antioxidant effects in the ROT Drosophila model by increasing GSH levels and decreasing ROS[1].
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[1]. Pandareesh MD, et al. Curcumin Monoglucoside Shows Improved Bioavailability and Mitigates Rotenone Induced Neurotoxicity in Cell and Drosophila Models of Parkinson's Disease. Neurochem Res. 2016 Nov
41(11):3113-3128. [Content Brief]
[2]. Li L M, et al. Antimicrobial and molecular interaction studies on derivatives of curcumin against Streptococcus pneumoniae which caused pneumonia[J]. Electronic Journal of Biotechnology, 2016, 19: 8-14.