Linagliptin-d3-1 MedChemExpress (MCE)

Product Name	Linagliptin-d3
Synonyms	Linagliptin-d3
CAS	1398044-48-8
EINECS
Chemical Formula	C25H25D3N8O2
Molecular Weight	475.56
inchi
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Descriptions	Linagliptin-d3-1 Linagliptin-d3-1 MedChemExpress (MCE) HY-10284S3 1398044-48-8 BI 1356-d3-1 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions Linagliptin-d3-1 Linagliptin-d3-1 MedChemExpress (MCE) HY-10284S3 1398044-48-8 BI 1356-d3-1 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Linagliptin-d3-1 (BI 1356-d3-1) is the deuterium labeled Linagliptin (HY-10284). Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM. \| \| \| \| \| \| \| \| \| \| [1]. Thomas L, et al. (R)-8-(3-amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione (BI 1356), a novel xanthine-based dipeptidyl peptidase 4 inhibitor, has a superior potency and longer duration of action [Content Brief] [2]. Eckhardt M, et al. 8-(3-(R)-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a highly potent, selective, long-acting, and orally bioavailable DPP-4 inhibitor for the treatment of type 2 d [Content Brief] [3]. Schurmann C, et al. The dipeptidyl peptidase-4 inhibitor linagliptin attenuates inflammation and accelerates epithelialization in wounds of diabetic ob/ob mice. J Pharmacol Exp Ther. 2012 Jul 342(1):71-80. [Content Brief] [4]. Huan Y, et al. The dual DPP4 inhibitor and GPR119 agonist HBK001 regulates glycemic control and beta cell function ex and in vivo. Sci Rep. 2017 Jun 28 7(1):4351. [Content Brief]
Supplier Website	https://www.medchemexpress.com/linagliptin-d3-1.html
Last Update	2025-05-21 16:50:25

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