Neuromedin U-25 (human) MedChemExpress (MCE)

Product Name	NEUROMEDIN U-25 (HUMAN)
Synonyms	NMU-25 (HUMAN) NEUROMEDIN U-25 (HUMAN) NeuroMedin U-25 (huMan)NMU-25 (huMan) Neuromedin U-25 (porcine) trifluoroacetate salt PHE-ARG-VAL-ASP-GLU-GLU-PHE-GLN-SER-PRO-PHE-ALA-SER-GLN-SER-ARG-GLY-TYR-PHE-LEU-PHE-ARG-PRO-ARG-ASN-NH2 Synonyms NMU-25 (HUMAN) NEUROMEDIN U-25 (HUMAN) NeuroMedin U-25 (huMan)NMU-25 (huMan) Neuromedin U-25 (porcine) trifluoroacetate salt PHE-ARG-VAL-ASP-GLU-GLU-PHE-GLN-SER-PRO-PHE-ALA-SER-GLN-SER-ARG-GLY-TYR-PHE-LEU-PHE-ARG-PRO-ARG-ASN-NH2 H-PHE-ARG-VAL-ASP-GLU-GLU-PHE-GLN-SER-PRO-PHE-ALA-SER-GLN-SER-ARG-GLY-TYR-PHE-LEU-PHE-ARG-PRO-ARG-ASN-NH2 L-Aspartamide, L-phenylalanyl-L-arginyl-L-valyl-L-α-aspartyl-L-α-glutamyl-L-α-glutamyl-L-phenylalanyl-L-glutaminyl-L-seryl-L-prolyl-L-phenylalanyl-L-alanyl-L-seryl-L-glutaminyl-L-seryl-L-arginylglycyl-L-tyrosyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-
CAS	312306-89-1
EINECS
Chemical Formula	C141H203N41O38
Molecular Weight	3080.37
inchi
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Descriptions	Neuromedin U-25 (human) Neuromedin U-25 (human) MedChemExpress (MCE) HY-P2378 312306-89-1 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions Neuromedin U-25 (human) Neuromedin U-25 (human) MedChemExpress (MCE) HY-P2378 312306-89-1 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Neuromedin U-25 human is the active form of neuromedin U in human. Neuromedin U-25 human inhibits glucose-stimulated insulin secretion, which leads to early-onset obesity. Neuromedin U-25 serves as vasoconstrictor in human vascular beds. Neuromedin U-25 human (4 pM-2 nM) binds to receptors in human left ventricle and coronary artery with KDs of 0.26 and 0.11 nM, respectively[1]. Neuromedin U-25 human (0.1 nM-0.1 μM) constricts coronary artery, mammary artery and saphenous vein endothelium-independently, with potency pD2s of 8.6, 8.0 and 8.2, respectively[1]. Phe-Arg-Val-Asp-Glu-Glu-Phe-Gln-Ser-Pro-Phe-Ala-Ser-Gln-Ser-Arg-Gly-Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2 \| \| \| \| \| \| \| \| \| \| [1]. Mitchell JD, et al., Expression and vasoconstrictor function of anorexigenic peptides neuromedin U-25 and S in the human cardiovascular system. Cardiovasc Res. 2009 Feb 1 81(2):353-61. [Content Brief] [2]. Alfa RW, et al., Suppression of insulin production and secretion by a decretin hormone. Cell Metab. 2015 Feb 3 21(2):323-334. [Content Brief]
Supplier Website	https://www.medchemexpress.com/neuromedin-u-25-human.html
Last Update	2025-05-21 16:50:25

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