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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product NameMezilamine
SynonymsMezilamine
4-Chloro-2-methylamino-5-methylthio-6-(4-methyl-1-piperazinyl)pyrimidine
N-Methyl-4-chloro-5-(methylthio)-6-(4-methylpiperazino)pyrimidine-2-amine
4-Chloro-N-methyl-6-(4-methylpiperazin-1-yl)-5-(methylthio)pyrimidin-2-amine

Synonyms

Mezilamine
4-Chloro-2-methylamino-5-methylthio-6-(4-methyl-1-piperazinyl)pyrimidine
N-Methyl-4-chloro-5-(methylthio)-6-(4-methylpiperazino)pyrimidine-2-amine
4-Chloro-N-methyl-6-(4-methylpiperazin-1-yl)-5-(methylthio)pyrimidin-2-amine
2-Pyrimidinamine, 4-chloro-N-methyl-6-(4-methyl-1-piperazinyl)-5-(methylthio)-
CAS50335-55-2
EINECS
Chemical FormulaC11H18ClN5S
Molecular Weight287.81
inchi
PackageInquiry
PriceGet quote
DescriptionsMezilamine

Mezilamine

MedChemExpress (MCE)

HY-119615

50335-55-2

Please store the product under the recommended conditions in the Certificate of Analysis.

Room temperature in continental US

Descriptions

Mezilamine

Mezilamine

MedChemExpress (MCE)

HY-119615

50335-55-2

Please store the product under the recommended conditions in the Certificate of Analysis.

Room temperature in continental US
may vary elsewhere.

Mezilamine is a potent antidopaminergic agent. Mezilamine induces a concentration dependent increase in the electrically stimulated overflow of 3H-noradrenaline from rat cortical slices, without affecting the basal overflow. Mezilamine acts as a presynaptic α-adrenoceptor antagonist and a postsynaptic α-adrenoceptor agonist.

Mezilamine (1, 5, 10 μM) causes a concentration-dependent increase in 3H-stimulated overflow, without affecting the spontaneous outflow from cortical slices[1].

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[1]. G Le Fur, et al. Mezilamine, a new dopamine antagonist, blocks presynaptic but stimulates postsynaptic alpha-adrenoceptors. Eur J Pharmacol. 1979 Oct 15
58(4):359-67.
[Content Brief]

Supplier Websitehttps://www.medchemexpress.com/mezilamine.html
Last Update2025-05-21 16:50:25
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