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Supplier NameMedChemExpress (MCE)
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Product Name3'-Azido-3'-deoxy-5-methylcytidine
Synonyms3'-Azido-3'-deoxy-5-methylcytidine;3'-Azido-3'-deoxy-5-methylcytidine
CAS1282040-14-5
EINECS
Chemical FormulaC10H14N6O4
Molecular Weight282.26
inchi
Package1 mg;5 mg;10 mg;25 mg;50 mg;100 mg
PriceGet quote
Descriptions3'-Azido-3'-deoxy-5-methylcytidine

3'-Azido-3'-deoxy-5-methylcytidine

MedChemExpress (MCE)

HY-111640

1282040-14-5

99.90%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year

Room temperature in continental US

Descriptions

3'-Azido-3'-deoxy-5-methylcytidine

3'-Azido-3'-deoxy-5-methylcytidine

MedChemExpress (MCE)

HY-111640

1282040-14-5

99.90%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year

Room temperature in continental US
may vary elsewhere.

3'-Azido-3'-deoxy-5-methylcytidine (CS-92) is a potent xenotropic murine leukemia-related retrovirus (XMRV) inhibitor with a CC50 of 43.5 μM in MCF-7 cells. 3'-Azido-3'-deoxy-5-methylcytidine also inhibits HIV-1 reverse transcriptase with an EC50 of 0.06 μM in peripheral blood mononuclear (PBM) cells. 3'-Azido-3'-deoxy-5-methylcytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HIV-1 0.06 μM (EC50, in PBM cells) XMRV 43.5 μM (CC50, in MCF-7 cells)

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[1]. Singh IR, et al. Raltegravir is a potent inhibitor of XMRV, a virus implicated in prostate cancer and chronic fatigue syndrome. PLoS One. 2010 Apr 1
5(4):e9948.
[Content Brief]

Supplier Websitehttps://www.medchemexpress.com/3_acute_-Azido-3_acute_-deoxy-5-methylcytidine.html
Last Update2025-05-21 16:50:25
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