MARK-IN-1 MedChemExpress (MCE)

Product Name	N-((1R,6R)-6-aMino-2,2-difluorocyclohexyl)-5-Methyl-4-(6-(1-Methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyriMidin-3-yl)thiophene-2-carboxaMide
Synonyms	MARK-IN-1 N-((1R,6R)-6-Amino-2,2-difluorocyclohexyl)-5-methyl-4-(6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a N-[(1R,6R)-6-amino-2,2-difluorocyclohexyl]-5-methyl-4-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-3-yl]thiophene-2-carboxamide Synonyms MARK-IN-1 N-((1R,6R)-6-Amino-2,2-difluorocyclohexyl)-5-methyl-4-(6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a N-[(1R,6R)-6-amino-2,2-difluorocyclohexyl]-5-methyl-4-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-3-yl]thiophene-2-carboxamide N-((1R,6R)-6-aMino-2,2-difluorocyclohexyl)-5-Methyl-4-(6-(1-Methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyriMidin-3-yl)thiophene-2-carboxaMide 2-Thiophenecarboxamide, N-[(1R,6R)-6-amino-2,2-difluorocyclohexyl]-5-methyl-4-[6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-3-yl]-
CAS	1109283-93-3
EINECS
Chemical Formula	C22H23F2N7OS
Molecular Weight	471.53
inchi
Package	1 mg
Price	Get quote
Descriptions	MARK-IN-1 MARK-IN-1 MedChemExpress (MCE) HY-101933 1109283-93-3 98.48% 4°C, protect from light In solvent : -80°C, 6 months Descriptions MARK-IN-1 MARK-IN-1 MedChemExpress (MCE) HY-101933 1109283-93-3 98.48% 4°C, protect from light In solvent : -80°C, 6 months -20°C, 1 month (protect from light) Room temperature in continental US may vary elsewhere. MARK-IN-1 is a potent microtubule affinity regulating kinase (MARK) inhibitor with an IC50 of <0.25 nM. MARK-IN-1 (Compound 25) is a potent MARK inhibitor. Inhibition of MARK represents a potentially attractive means of arresting neurofibrillary tangle pathology in Alzheimer's disease[1]. IC50: [1] In Vitro MARK-IN-1 (Compound 25) is a potent MARK inhibitor. Inhibition of MARK represents a potentially attractive means of arresting neurofibrillary tangle pathology in Alzheimer's disease[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> MARK-IN-1 Related Antibodies \| \| \| \| \| \| \| \| \| \| [1]. Sloman DL, et al. Optimization of microtubule affinity regulating kinase (MARK) inhibitors with improved physical properties. Bioorg Med Chem Lett. 2016 Sep 1 26(17):4362-6. [Content Brief]
Supplier Website	https://www.medchemexpress.com/MARK-IN-1.html
Last Update	2025-05-21 16:50:25

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