HIV-1 integrase inhibitor 3 MedChemExpress (MCE)

Product Name	HIV-1 integrase inhibitor 3
Synonyms	1638504-56-9;HIV-1 integrase inhibitor 3;1,8-Naphthyridine-3-carboxamide, 4-amino-N-[(2,4-difluorophenyl)methyl]-1,2-dihydro-1-hydroxy-6-(5-hydroxypentyl)-2-oxo-
CAS	1638504-56-9
EINECS
Chemical Formula	C21H22F2N4O4
Molecular Weight	432.42
inchi
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Descriptions	HIV-1 integrase inhibitor 3 HIV-1 integrase inhibitor 3 MedChemExpress (MCE) HY-108817 1638504-56-9 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions HIV-1 integrase inhibitor 3 HIV-1 integrase inhibitor 3 MedChemExpress (MCE) HY-108817 1638504-56-9 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. HIV-1 integrase inhibitor 3 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM. HIV-1 integrase inhibitor 3 (compound 4c) is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM. HIV-1 integrase inhibitor 3 also displays an antiviral inhibitory potency against the Q148H/G140S mutant with an EC50 of 7 nM[1]. IC50: 2.7 nM (INST)[1] Cellular Effect Cell Line Type Value Description References \| \| \| \| \| \| \| \| \| \| [1]. Zhao XZ, et al. HIV-1 Integrase Strand Transfer Inhibitors with Reduced Susceptibility to Drug Resistant MutantIntegrases. ACS Chem Biol. 2016 Apr 15 11(4):1074-81. [Content Brief]
Supplier Website	https://www.medchemexpress.com/HIV-1_integrase_inhibitor_3.html
Last Update	2025-05-21 16:50:25

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