TCS 359 MedChemExpress (MCE)

Product Name	TCS 359
Synonyms	TCS359 TCS 359 Flt-3 inhibitor 2-(3,4-DIMETHOXY-BENZOYLAMINO)-4,5,6,7-T 2-[(3,4-Dimethoxybenzoyl)amino]-4,5,6,7-benzo[b]thiophene-3-carboxamide 2-(3,4-diMethoxybenzaMido)- 4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxaMide Synonyms TCS359 TCS 359 Flt-3 inhibitor 2-(3,4-DIMETHOXY-BENZOYLAMINO)-4,5,6,7-T 2-[(3,4-Dimethoxybenzoyl)amino]-4,5,6,7-benzo[b]thiophene-3-carboxamide 2-(3,4-diMethoxybenzaMido)- 4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxaMide 2-[(3,4-Dimethoxybenzoyl)amino]-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxamide Benzo[b]thiophene-3-carboxaMide,2-[(3,4-diMethoxybenzoyl)aMino]-4,5,6,7-tetrahydro- 2-(3,4-Dimethoxy-benzoylamino)-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid amide
CAS	301305-73-7
EINECS
Chemical Formula	C18H20N2O4S
Molecular Weight	360.43
inchi
Package	10 mM * 1 mL;5 mg;10 mg;50 mg
Price	Get quote
Descriptions	TCS 359 TCS 359 MedChemExpress (MCE) HY-13907 301305-73-7 99.89% 4°C, protect from light In solvent : -80°C, 6 months Descriptions TCS 359 TCS 359 MedChemExpress (MCE) HY-13907 301305-73-7 99.89% 4°C, protect from light In solvent : -80°C, 6 months -20°C, 1 month (protect from light) Room temperature in continental US may vary elsewhere. TCS 359, a 2-acylaminothiophene-3-carboxamide, is a potent and selective FLT3 inhibitor with an IC50 of 42 nM. TCS 359 inhibits MV4-11 cell proliferation with an IC50 of 340 nM. IC50: 42 nM (FLT3)[1] Cellular Effect Cell Line Type Value Description References \| \| \| \| \| \| \| \| \| \| [1]. Patch RJ, et al. Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3. Bioorg Med Chem Lett. 2006 Jun 15 16(12):3282-6. [Content Brief]
Supplier Website	https://www.medchemexpress.com/tcs-359.html
Last Update	2025-05-21 16:50:25

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