Apyramide MedChemExpress (MCE)

Product Name	Apyramide
Synonyms	Apyramide
CAS	68483-33-0
EINECS
Chemical Formula	C27H23ClN2O5
Molecular Weight	490.93
inchi
Package	5 mg;10 mg;20 mg
Price	Get quote
Descriptions	Apyramide Apyramide MedChemExpress (MCE) HY-U00046 68483-33-0 99.06% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions Apyramide Apyramide MedChemExpress (MCE) HY-U00046 68483-33-0 99.06% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. Apyramide is an anti-inflammatory agent (NSAID) and behaves as a proagent of indomethacin (HY-14397). Indomethacin is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2. Apyramide is far less toxic than indomethacin in rats and mice by the oral or the i.p. route. It exhibits anti-inflammatory activity on carrageenin-induced paw oedema, cotton pellet granuloma and adjuvant arthritis, as well as analgesic and antipyretic activities[1]. \| \| \| \| \| \| \| \| \| \| [1]. Sauvaire D, et al. Pharmacological activity and toxicity of apyramide: comparison with non-steroidal anti-inflammatory agents. Drugs Exp Clin Res. 1987 13(5):247-52. [Content Brief] [2]. M Cociglio, et al. Pharmacokinetics of an indomethacin pro-drug: apyramide after intravenous administration in dog. Eur J Drug Metab Pharmacokinet. Oct-Dec 1991 16(4):275-80. [Content Brief]
Supplier Website	https://www.medchemexpress.com/Apyramide.html
Last Update	2025-05-21 16:50:25

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