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Supplier NameMedChemExpress (MCE)
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Product NameBenzenemethanamine, 3-[[4-(2,3-dihydro-1,4-benzodioxin-5-yl)-2-methoxyphenyl]amino]-N,N-dimethyl-
SynonymsBenzenemethanamine, 3-[[4-(2,3-dihydro-1,4-benzodioxin-5-yl)-2-methoxyphenyl]amino]-N,N-dimethyl-
Compound 3344
4-(2,3-dihydro-1,4-benzodioxin-5-yl)-N-[3-[(dimethylamino)methyl]phenyl]-2-methoxyaniline
CAS2368246-78-8
EINECS
Chemical FormulaC24H26N2O3
Molecular Weight390.47
inchi
PackageInquiry
PriceGet quote
Descriptionspan-KRAS-IN-16

pan-KRAS-IN-16

MedChemExpress (MCE)

HY-164645

2368246-78-8

Please store the product under the recommended conditions in the Certificate of Analysis.

Room temperature in continental US

Descriptions

pan-KRAS-IN-16

pan-KRAS-IN-16

MedChemExpress (MCE)

HY-164645

2368246-78-8

Please store the product under the recommended conditions in the Certificate of Analysis.

Room temperature in continental US
may vary elsewhere.

pan-KRAS-IN-16 (Compound 3344) is an anti-RAS small molecule derived from an intracellular antibody fragment with pan-RAS-effector protein-protein interaction inhibitor properties. pan-KRAS-IN-16 binds to a hydrophobic pocket near to the effector-binding switch regions of RAS. pan-KRAS-IN-16 prevents endogenous RAS-dependent signaling in tumor cell lines.

KRas G12D H-Ras Ras

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[1]. Bery N, et al. BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions. Elife. 2018 Jul 10
7:e37122.
[Content Brief]

Supplier Websitehttps://www.medchemexpress.com/pan-kras-in-16.html
Last Update2025-05-21 16:50:25
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