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Supplier NameMedChemExpress (MCE)
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Emailsales@medchemexpress.com; tech@medchemexpress.com
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Product Name8-deazahomofolic acid
Synonyms8-deazahomofolic acid;L-Glutamic acid, N-[4-[[2-(2-amino-1,4-dihydro-4-oxopyrido[3,2-d]pyrimidin-6-yl)ethyl]amino]benzoyl]- (9CI)
CAS111113-73-6
EINECS
Chemical FormulaC21H22N6O6
Molecular Weight454.44
inchi
PackageInquiry
PriceGet quote
Descriptions8-Deazahomofolic acid

8-Deazahomofolic acid

MedChemExpress (MCE)

HY-124093

111113-73-6

Please store the product under the recommended conditions in the Certificate of Analysis.

Room temperature in continental US

Descriptions

8-Deazahomofolic acid

8-Deazahomofolic acid

MedChemExpress (MCE)

HY-124093

111113-73-6

Please store the product under the recommended conditions in the Certificate of Analysis.

Room temperature in continental US
may vary elsewhere.

8-Deazahomofolic acid is an inhibitor of thymidylate synthase (TS) and other folate-related enzymes. 8-Deazahomofolic acid shows inhibitory activity against folate-dependent S. faecium, L. casei, and MTX (HY-14519) resistant strains. 8-Deazahomofolic acid also inhibits the growth of L1210 leukemia cells, with an IC50 value of 87.5 μM. 8-Deazahomofolic acid can be used in research on bacterial infections and tumors.

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[1]. DeGraw JI, et al. Synthesis and biological evaluation of 8-deazahomofolic acid and its tetrahydro derivative. J Med Chem. 1988 Jan
31(1):150-3. [Content Brief]

Supplier Websitehttps://www.medchemexpress.com/8-deazahomofolic-acid.html
Last Update2025-05-21 16:50:25
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