DAPD-NHc-pr MedChemExpress (MCE)

Product Name	(2R,4R)-4-[2-Amino-6-(cyclopropylamino)purin-9-yl]-1,3-dioxolan-2-yl]methanol
Synonyms	(2R,4R)-4-[2-Amino-6-(cyclopropylamino)purin-9-yl]-1,3-dioxolan-2-yl]methanol BCH 13520 BCH13520 BCH-13520 SPD 756 SPD756 SPD-756 Synonyms (2R,4R)-4-[2-Amino-6-(cyclopropylamino)purin-9-yl]-1,3-dioxolan-2-yl]methanol BCH 13520 BCH13520 BCH-13520 SPD 756 SPD756 SPD-756 (-)-(2R,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-1,3-dioxolane-2-methanol
CAS	280138-71-8
EINECS
Chemical Formula	C12H16N6O3
Molecular Weight	292.29
inchi
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Descriptions	DAPD-NHc-pr DAPD-NHc-pr MedChemExpress (MCE) HY-117105 280138-71-8 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions DAPD-NHc-pr DAPD-NHc-pr MedChemExpress (MCE) HY-117105 280138-71-8 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. DAPD-NHc-pr (compound 12) is an HIV inhibitor with EC50/EC90 values of 0.85 μM and 13 μM, respectively. DAPD-NHc-pr shows no toxicity to normal cells (PBM, CEM, VERO). EC50: 0.85 μM (HIV)[1] Molecular Weight 292.29 \| \| \| \| \| \| \| \| \| \| [1]. Narayanasamy J, et al. Synthesis and anti-HIV activity of (-)-beta-D-(2R,4R)-1,3-dioxolane-2,6-diamino purine (DAPD) (amdoxovir) and (-)-beta-D-(2R,4R)-1,3-dioxolane guanosine (DXG) prodrugs. Antiviral Res. 2007 Sep 75(3):198-209. [Content Brief]
Supplier Website	https://www.medchemexpress.com/dapd-nhc-pr.html
Last Update	2025-05-21 16:50:25

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