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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product Name1,2,3,4-Tetrahydro Staurosporin
Synonyms1,2,3,4-Tetrahydro Staurosporin
CAS220038-19-7
EINECS
Chemical FormulaC28H30N4O3
Molecular Weight470.56
inchi
Package1 mg
PriceGet quote
Descriptions1,2,3,4-Tetrahydro Staurosporin

1,2,3,4-Tetrahydro Staurosporin

MedChemExpress (MCE)

HY-W740378

220038-19-7

AFN-941

Please store the product under the recommended conditions in the Certificate of Analysis.

Room temperature in continental US

Descriptions

1,2,3,4-Tetrahydro Staurosporin

1,2,3,4-Tetrahydro Staurosporin

MedChemExpress (MCE)

HY-W740378

220038-19-7

AFN-941

Please store the product under the recommended conditions in the Certificate of Analysis.

Room temperature in continental US
may vary elsewhere.

1,2,3,4-Tetrahydrostaurosporine is a derivative of Staurosporine (HY-15141) and an inhibitor of mutant EGFR (IC50=74 nM for EGFRT790M). It is selective for EGFRT790M over wild-type EGFR (IC50=390 nM). It also binds to Janus kinase 3 (JAK3).

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[1]. Song, et al. Staurosporine scaffold-based rational discovery of the wild-type sparing reversible inhibitors of EGFR T790M gatekeeper mutant in lung cancer with analog-sensitive kinase technology. J. Mol. Recognit. 30(4):e2590,(2017).

Supplier Websitehttps://www.medchemexpress.com/1-2-3-4-tetrahydro-staurosporin.html
Last Update2025-04-01 14:45:47
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