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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product NameIzonsteride
SynonymsLY320236
LY-320236
IZONSTERIDE
Izonsteride
UNII-A5E8C36F34
(4aR,10bR)-8-[(4-Ethyl-2-benzothiazolyl)thio]-1,4,4a,5,6,10b-hexahydro-4,10b-dimethylbenzo[f]quinolin-3(2H)-one
(4aR,10bR)-8-(4-Ethylbenzothiazol-2-ylsulfanyl)-4,10b-dimethyl-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinolin-3-one
CAS176975-26-1
EINECS
Chemical FormulaC24H26N2OS2
Molecular Weight422.61
inchi
PackageInquiry
PriceGet quote
DescriptionsIzonsteride

Izonsteride

MedChemExpress (MCE)

HY-106129

176975-26-1

LY 320236

Please store the product under the recommended conditions in the Certificate of Analysis.

Room temperature in continental US

Descriptions

Izonsteride

Izonsteride

MedChemExpress (MCE)

HY-106129

176975-26-1

LY 320236

Please store the product under the recommended conditions in the Certificate of Analysis.

Room temperature in continental US
may vary elsewhere.

Izonsteride (Compound LY320236) is an inhibitor of 5α-reductase (IC50 = 11.6 nM for type I
7.37 nM for type II). LY320236 inhibits the activity of steroid 5α-reductase, preventing the conversion of testosterone (T) to dihydrotestosterone (DHT). LY320236 can significantly inhibit the growth of LNCaP tumors in thymic mice without exhibiting obvious host toxicity.

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[1]. McNulty AM, et al. Kinetic analysis of LY320236: competitive inhibitor of type I and non-competitive inhibitor of type II human steroid 5alpha-reductase. J Steroid Biochem Mol Biol. 2000 Jan-Feb
72(1-2):13-21.
[Content Brief]

Supplier Websitehttps://www.medchemexpress.com/izonsteride.html
Last Update2025-05-21 16:50:25
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