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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product Name1,2-Ethanediamine, N1-[5-chloro-6-methyl-2-(2-pyridinyl)-4-pyrimidinyl]-N2-[6-(trifluoromethyl)-2-pyridinyl]-
Synonyms1,2-Ethanediamine, N1-[5-chloro-6-methyl-2-(2-pyridinyl)-4-pyrimidinyl]-N2-[6-(trifluoromethyl)-2-pyridinyl]-
RDR 03871
RDR03871
RDR-03871
N'-[5-chloro-6-methyl-2-(2-pyridinyl)-4-pyrimidinyl]-N-[6-(trifluoromethyl)-2-pyridinyl]ethane-1,2-diamine
CAS286008-51-3
EINECS
Chemical FormulaC18H16ClF3N6
Molecular Weight408.81
inchi
PackageInquiry
PriceGet quote
DescriptionsRDR03871

RDR03871

MedChemExpress (MCE)

HY-123544

286008-51-3

Please store the product under the recommended conditions in the Certificate of Analysis.

Room temperature in continental US

Descriptions

RDR03871

RDR03871

MedChemExpress (MCE)

HY-123544

286008-51-3

Please store the product under the recommended conditions in the Certificate of Analysis.

Room temperature in continental US
may vary elsewhere.

RDR03871 (compound 2) is a potent dual MDM2/MDM4 inhibitor with IC50 values of 35.4 nM and 10.4 nM for MDM2-p53 and MDM4-p53, respectively.

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[1]. Mariateresa Giustiniano, et al. Computer-Aided Identification and Lead Optimization of Dual Murine Double Minute 2 and 4 Binders: Structure-Activity Relationship Studies and Pharmacological Activity. J Med Chem. 2017 Oct 12
60(19):8115-8130.
[Content Brief]

Supplier Websitehttps://www.medchemexpress.com/rdr03871.html
Last Update2025-05-21 16:50:25
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