Acetylcysteine-d3 MedChemExpress (MCE)

Product Name	N-Acetyl-d3-L-cysteine
Synonyms	Acetylcysteine-d3 N-Acetylcysteine-d3 N-Acetyl-L-cysteine-d3 N-Acetyl-d3-L-cysteine [2H3]-N-Acetyl-L-cysteine L-Cysteine, N-(acetyl-d3)- (9CI) N-ACETYL-L-CYSTEINE-D3 (ACETYLCYSTEINE-D3) Synonyms Acetylcysteine-d3 N-Acetylcysteine-d3 N-Acetyl-L-cysteine-d3 N-Acetyl-d3-L-cysteine [2H3]-N-Acetyl-L-cysteine L-Cysteine, N-(acetyl-d3)- (9CI) N-ACETYL-L-CYSTEINE-D3 (ACETYLCYSTEINE-D3) N-Acetyl-L-Cysteine-d3 (Acetylcysteine-d3)
CAS	131685-11-5
EINECS
Chemical Formula	C5H6D3NO3S
Molecular Weight	166.21
inchi
Package	1 mg
Price	Email to quote
Descriptions	Acetylcysteine-d3 Acetylcysteine-d3 MedChemExpress (MCE) HY-B0215S 131685-11-5 N-Acetylcysteine-d3 Descriptions Acetylcysteine-d3 Acetylcysteine-d3 MedChemExpress (MCE) HY-B0215S 131685-11-5 N-Acetylcysteine-d3 N-Acetyl-L-cysteine-d3 NAC-d3 97.02% 4°C, protect from light, stored under nitrogen In solvent : -80°C, 6 months -20°C, 1 month (protect from light, stored under nitrogen) Room temperature in continental US may vary elsewhere. Acetylcysteine-d3 is the deuterium labeled Acetylcysteine. Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine is the most stable form of cysteine during drug delivery and can be used in disulfidptosis studies. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. \| \| \| \| \| \| \| \| \| \| [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 53(2):211-216. [Content Brief]* [2]. Halasi M, et al. ROS inhibitor N-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors. Biochem J. 2013 Sep 1 454(2):201-8. [Content Brief] [3]. Ferrari G, et al. N-acetylcysteine (D- and L-stereoisomers) prevents apoptotic death of neuronal cells. J Neurosci. 1995 Apr 15(4):2857-66. [Content Brief] [4]. Tsai JC, et al. Induction of apoptosis by pyrrolidinedithiocarbamate and N-acetylcysteine in vascular smooth muscle cells. J Biol Chem. 1996 Feb 16 271(7):3667-70. [Content Brief] [5]. Yan CY, et al. Prevention of PC12 cell death by N-acetylcysteine requires activation of the Ras pathway. J Neurosci. 1998 Jun 1 18(11):4042-9. [Content Brief] [6]. Farr SA, et al. The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice. J Neurochem. 2003 Mar 84(5):1173-83. [Content Brief] [7]. Kalimeris K, et al. N-acetylcysteine ameliorates liver injury in a rat model of intestinal ischemia reperfusion. J Surg Res. 2016 Dec 206(2):263-272. [Content Brief] [8]. Garigliany MM, et al. N-acetylcysteine lacks universal inhibitory activity against influenza A viruses. J Negat Results Biomed. 2011 May 9 10:5. [Content Brief] [9]. Gu Q, et al. Disulfidptosis, a novel cell death pathway: molecular landscape and therapeutic implications[J]. Aging Dis, 2024, 10. [Content Brief]
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Last Update	2025-05-21 16:50:25

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