OMDM-1 MedChemExpress (MCE)

Product Name	OMDM-1
Synonyms	OMDM-1
CAS	616884-62-9
EINECS
Chemical Formula	C27H45NO3
Molecular Weight	431.6511
inchi
Package	1 mg;5 mg;10 mg
Price	Email to quote
Descriptions	OMDM-1 OMDM-1 MedChemExpress (MCE) HY-121557 616884-62-9 98.05% -20°C, sealed storage, away from moisture In solvent : -80°C, 6 months Descriptions OMDM-1 OMDM-1 MedChemExpress (MCE) HY-121557 616884-62-9 98.05% -20°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. OMDM-1 is a potent, selective and metabolically stable inhibitor of anandamide cellular uptake (ACU), with a Ki of 2.4 μM. OMDM-1 shows poor affinity for either CB1 (Ki=12.1 μM) or CB2 (Ki>10 μM) receptors in rat brain and spleen membranes, respectively OMDM-1 has almost no activity at vanilloid receptors in the intracellular calcium assay carried out with intact cells over-expressing the human VR1 (EC50≥10 μM), and no activity as inhibitors of FAAH in N18TG2 cell membranes (Ki>50 μM)[1]. Ki: 2.4 μM (anandamide cellular uptake)[1] In Vitro OMDM-1 shows poor affinity for either CB1 (Ki=12.1 μM) or CB2 (Ki>10 μM) receptors in rat brain and spleen membranes, respectively OMDM-1 has almost no activity at vanilloid receptors in the intracellular calcium assay carried out with intact cells over-expressing the human VR1 (EC50≥10 μM), and no activity as inhibitors of FAAH in N18TG2 cell membranes (Ki>50 μM)[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> OMDM-1 Related Antibodies \| \| \| \| \| \| \| \| \| \| [1]. Ortar G, et al. Novel selective and metabolically stable inhibitors of anandamide cellular uptake. Biochem Pharmacol. 2003 May 1 65(9):1473-81. [Content Brief]
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Last Update	2025-05-21 16:50:25

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