Cyclo(-RGDfK) TFA MedChemExpress (MCE)

Product Name	Cyclo(-RGDfK) Trifluoroacetate
Synonyms	Cyclo(-RGDfK) Trifluoroacetate
CAS	500577-51-5
EINECS
Chemical Formula	C29H42F3N9O9
Molecular Weight	717.69
inchi
Package	1 mg;5 mg;10 mg;25 mg;50 mg
Price	Email to quote
Descriptions	Cyclo(-RGDfK) TFA Cyclo(-RGDfK) TFA MedChemExpress (MCE) HY-P0023A 500577-51-5 99.82% Sealed storage, away from moisture Powder -80°C 2 years -20°C 1 year In solvent : -80°C, 6 months Descriptions Cyclo(-RGDfK) TFA Cyclo(-RGDfK) TFA MedChemExpress (MCE) HY-P0023A 500577-51-5 99.82% Sealed storage, away from moisture Powder -80°C 2 years -20°C 1 year In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Cyclo(-RGDfK) TFA is a potent and selective inhibitor of the αvβ3 integrin, with an IC50 of 0.94 nM. Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface. Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin and exhibits a IC50 of 0.94 nM[1].[66Ga]DOTA-E-[c(RGDfK)]2 can be prepared with high radiochemical purity (>97%), specific activity (36-67GBq/μM), in vitro stability, and moderate protein binding. MicroPET imaging up to 24 post-injection showed contrasting tumors reflecting αvβ3-targeted tracer accumulation[2]. αvβ3 0.94 nM (IC50) \| \| \| \| \| \| \| \| \| \| [1]. Simecek J, et al. Benefits of NOPO as chelator in gallium-68 peptides, exemplified by preclinical characterization of (68)Ga-NOPO-c(RGDfK). Mol Pharm. 2014 May 5 11(5):1687-95. [Content Brief] [2]. Lopez-Rodriguez V, et al. Preparation and preclinical evaluation of (66)Ga-DOTA-E(c(RGDfK))2 as a potential theranostic radiopharmaceutical. Nucl Med Biol. 2015 Feb 42(2):109-14. [Content Brief]
Supplier Website	https://www.medchemexpress.com/cyclo-rgdfk-tfa.html
Last Update	2025-05-21 16:50:25

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