Asperphenamate MedChemExpress (MCE)

Product Name	ASPERPHENAMATE
Synonyms	Auranamide;ASPERPHENAMATE;N-Benzoyl-L-phenylalanine (S)-2-benzoylamino-3-phenylpropyl ester;(2S)-2-(Benzoylamino)-3-phenylpropanoic acid (2S)-2-(benzoylamino)-3-phenylpropyl ester
CAS	63631-36-7
EINECS
Chemical Formula	C32H30N2O4
Molecular Weight	506.59
inchi
Package	10 mM * 1 mL;1 mg;5 mg;10 mg
Price	Email to quote
Descriptions	Asperphenamate Asperphenamate MedChemExpress (MCE) HY-129578 63631-36-7 98.0% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions Asperphenamate Asperphenamate MedChemExpress (MCE) HY-129578 63631-36-7 98.0% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. Asperphenamate, a fungal metabolite of Aspergillus flatiipes with anti-cancer effect, exhibits IC50 values of 92.3 μM, 96.5 μM and 97.9 μM in T47D, MDA-MB-231 and HL-60 cells, respectively. Asperphenamate can inhibit cancer cell proliferation by fully inducing autophagy. asperphenamate showed inhibition effects against cathepsin L. At the same time, it also displayed weak inhibitory ability against cathepsin S. \| \| \| \| \| \| \| \| \| \| [1]. Alice M.Clark, et al. Synthesis of asperphenamate, a novel fungal metabolite. Phytochemistry [2]. LeiYuan, et al. Total synthesis and anticancer activity studies of the stereoisomers of asperphenamate and patriscabratine. Chinese Chemical Letters Volume 21, Issue 2, February 2010, Pages 155-158. [3]. Yuan L, et al. Discovery of novel cathepsin inhibitors with potent anti-metastatic effects in breast cancer cells. Bioorg Chem. 2018 Dec 81:672-680. [Content Brief]
Supplier Website	https://www.medchemexpress.com/asperphenamate.html
Last Update	2025-04-01 14:45:47

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