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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product Name1-(1,8-dihydroxy-3-methylnaphthalen-2-yl)ethanone
Synonymsmusizin
Nepodin
nepodin
Musizin
Musizine
NSC 365795
Dianellidin

Synonyms

musizin
Nepodin
nepodin
Musizin
Musizine
NSC 365795
Dianellidin
NEPODIN (MUSIZIN)
2-Acetyl-3-methyl-1,8-naphthalenediol
1-(1,8-Dihydroxy-3-methyl-2-naphthyl)ethanone
1-(1,8-dihydroxy-3-methylnaphthalen-2-yl)ethanone
1-(1,8-Dihydroxy-3-methyl-2-naphthalenyl)ethanone
1-(1,8-dihydroxy-3-methyl-naphthalen-2-yl)ethanone
Ethanone,1-(1,8-dihydroxy-3-methyl-2-naphthalenyl)-
Ethanone, 1-(1,8-dihydroxy-3-methyl-2-naphthalenyl)-
CAS3785-24-8
EINECS
Chemical FormulaC13H12O3
Molecular Weight216.23
inchiInChI=1/C13H12O3/c1-7-6-9-4-3-5-10(15)12(9)13(16)11(7)8(2)14/h3-6,15-16H,1-2H3
Package1 mg;5 mg;10 mg;25 mg
PriceEmail to quote
DescriptionsNepodin

Nepodin

MedChemExpress (MCE)

HY-N5018

3785-24-8

Musizin

99.71%

4°C, protect from light *In solvent : -80°C, 6 months

Descriptions

Nepodin

Nepodin

MedChemExpress (MCE)

HY-N5018

3785-24-8

Musizin

99.71%

4°C, protect from light *In solvent : -80°C, 6 months
-20°C, 1 month (protect from light)

Room temperature in continental US
may vary elsewhere.

Nepodin (Musizin) is a quinone oxidoreductase (PfNDH2) inhibitor isolate from Rumex crispus.Nepodin (Musizin) stimulates the translocation of GLUT4 to the plasma membrane by activation of AMPK.Nepodin (Musizin) has antidiabetic and antimalarial activities.

Nepodin (Musizin) exhibits significant IC50 values that are 0.74 and 0.79 μg/ml against P. falciparum chloroquine-sensitive (3D7) and P. falciparum chloroquine-resistant (S20), respectively[1].

Nepodin (Musizin) (orally administration
2-10 mg/kg
4 weeks) improves the impaired glucose tolerance of db/db mice, also decreases an increase in plasma insulin concentration of db/db mice in a dose-dependent manner[2].

Plasmodium

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[1]. Lee KH, et al. Antimalarial activity of nepodin isolated from Rumex crispus. Arch Pharm Res. 2013 Apr
36(4):430-5.
[Content Brief]

[2]. Ha BG, et al. Antidiabetic effect of nepodin, a component of Rumex roots, and its modes of action in vitro and in vivo. Biofactors. 2014 Jul-Aug
40(4):436-47.
[Content Brief]

Supplier Websitehttps://www.medchemexpress.com/nepodin.html
Last Update2025-04-01 14:45:47
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