ATP disodium salt hydrate MedChemExpress (MCE)

Product Name	Adenosine-5'-triphosphate disodium salt hydrate
Synonyms	Adenosine Impurity 9 5μ-ATP-Na2, ATP hydrate disodium salt Adenosine-5'-triphosphate disodium salt hydrate Adenosine 5′-triphosphate disodium salt hydrate,ATP disodium salt Adenosine 5′-triphosphate disodium salt hydrate,5′-ATP-Na2, ATP disodium salt hydrate
CAS	34369-07-8
EINECS	213-579-1
Chemical Formula	C10H19N5NaO14P3
Molecular Weight	549.19
inchi	InChI=1/C10H16N5O13P3.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20 /h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20) /q inchi InChI=1/C10H16N5O13P3.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20 /h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20) /q 2*+1/p-2/t4-,6-,7-,10? /m1../s1
Package	500 mg;1 g;5 g
Price	Email to quote
Descriptions	ATP disodium salt hydrate ATP disodium salt hydrate MedChemExpress (MCE) HY-W010735 34369-07-8 Adenosine 5'-triphosphate disodium salt hydrate 98.0% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months Descriptions ATP disodium salt hydrate ATP disodium salt hydrate MedChemExpress (MCE) HY-W010735 34369-07-8 Adenosine 5'-triphosphate disodium salt hydrate 98.0% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. ATP disodium salt hydrate (Adenosine 5'-triphosphatedisodium salt hydrate) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt hydrate is an important endogenous signaling molecule in immunity and inflammation. ATP disodium salt hydrate (5mM 1 hour) co-treatment with LPS (1 μg/ml) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs[3].?ATP disodium salt hydrate (2 mM 0.5-24 hours) induces secretion of interleukin 1β, KC and MIP-2 from bone marrow derived macrophages (BMDMs) in vitro in a caspase-1 activation-dependent manner[4].?ATP disodium salt hydrate stimulats cytokine and chemokine secretion and inflammasome activation directly and indirectly induces in vitro neutrophil chemotaxis[4]. ATP disodium salt hydrate (50 mg/kg i.p.) protects mice against bacterial infection in vivo[4].?ATP disodium salt hydrate induces the secretion of IL1β, KC and MIP-2 and neutrophils recruitment in vivo[4]. Human Endogenous Metabolite \| \| \| \| \| \| \| \| \| \| [1]. Bonora M, et al. ATP synthesis and storage. Purinergic Signal. 2012 Sep 8(3):343-57. [Content Brief] [2]. M J L Bours, et al. Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. Pharmacol Ther. 2006 Nov 112(2):358-404. [Content Brief] [3]. Shuo Xu, et al. Doxycycline inhibits NAcht Leucine-rich repeat Protein 3 inflammasome activation and interleukin-1β production induced by Porphyromonas gingivalis-lipopolysaccharide and adenosine triphosphate in human gingival fibroblasts. Arch Oral Biol. 2019 Nov 107:104514. [Content Brief] [4]. Yang Xiang, et al. Adenosine-5'-Triphosphate (ATP) Protects Mice against Bacterial Infection by Activation of the NLRP3 Inflammasome. PLoS One. 2013 8(5): e63759. [Content Brief]
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Last Update	2025-05-21 16:50:25

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