Duramycin MedChemExpress (MCE)

Product Name	Lancovutide
Synonyms	Lancovutide
CAS	1391-36-2
EINECS
Chemical Formula	C88H123N23O25S3
Molecular Weight	2013.28
inchi
Package	1 mg;5 mg
Price	Email to quote
Descriptions	Duramycin Duramycin MedChemExpress (MCE) HY-106302 1391-36-2 Moli1901 Descriptions Duramycin Duramycin MedChemExpress (MCE) HY-106302 1391-36-2 Moli1901 Lancovutide 99.46% Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. Duramycin (Moli1901) is a lantibiotic derived from Streptomyces cinnamoneuma. Duramycin also is a antimicrobial peptide. Duramycin can be used for the research of cystic fibrosis (CF). Evaluation of [68Ga]NODAGA-Duramycin as a positron emission tomography (PET) tracer of cell death for whole-body detection of chemotherapy-induced organ toxicity. Organ uptake is analyzed in untreated and doxorubicin, busulfan, and cisplatin-treated mice 2 h after intravenous injection of [68Ga]NODAGA-Duramycin. [68Ga]NODAGA-Duramycin PET/CT is successfully applied to non-invasively detect chemotherapy-induced organ toxicity with high sensitivity in mice[3]. Cys-Lys-Gln-Cys-Cys-Ala-Phe-Gly-Pro-Phe-{Abu}-Phe-Val-Cys-Asp-Gly-Asn-{Abu}-Lys-NH2 (Disulfide bridge: Cys1-Abu18, Cys4-Cys14, Cys5-Abu11) \| \| \| \| \| \| \| \| \| \| [1]. Oliynyk I, et al. Effect of duramycin on chloride transport and intracellular calcium concentration in cystic fibrosis and non-cystic fibrosis epithelia. APMIS. 2010 Dec 118(12):982-90. [Content Brief] [2]. Huo L, et al. Insights into the Biosynthesis of Duramycin. Appl Environ Microbiol. 2017 Jan 17 83(3). pii: e02698-16. [Content Brief]
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Last Update	2025-05-21 16:50:25

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