EnlimomabEnlimomab
MedChemExpress (MCE)
HY-P99336
142864-19-5
BI-RR 0001
Anti-Human IL6 Recombinant Antibody
95.00%
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Enlimomab (BI-RR 0001), a murine IgG2a monoclonal antibody to the human ICAM-1, inhibits leukocyte adhesion to the vascular endothelium, thereby decreasing leukocyte extravasation and inflammatory tissue injury. Enlimomab has anti-inflammatory effects, and can be used for stroke research .
In whole blood, Enlimomab activates resting neutrophils in a complement-dependent manner[1] .
Mouse
Mouse IgG2a kappa
Mouse IgG2a kappa, Isotype Control
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[1]. J Vuorte, et al. Anti-ICAM-1 monoclonal antibody R6.5 (Enlimomab) promotes activation of neutrophils in whole blood. J Immunol. 1999 Feb 15
162(4):2353-7. [Content Brief]
[2]. [2]Gregory J del Zoppo. Acute anti-inflammatory approaches to ischemic stroke. Ann N Y Acad Sci. 2010 Oct
1207:143-8. [Content Brief]