Ocaratuzumab MedChemExpress (MCE)

Product Name	Ocaratuzumab
Synonyms	Ocaratuzumab
CAS	1169956-08-4
EINECS
Chemical Formula
Molecular Weight
inchi
Package	1 mg;5 mg
Price	Email to quote
Descriptions	Ocaratuzumab Ocaratuzumab MedChemExpress (MCE) HY-P99308 1169956-08-4 AME 133v Descriptions Ocaratuzumab Ocaratuzumab MedChemExpress (MCE) HY-P99308 1169956-08-4 AME 133v LY 2469298 Humanized Anti-MS4A1 Recombinant Antibody 95.00% Please store the product under the recommended conditions in the Certificate of Analysis. Ocaratuzumab (AME 133v) is an Fc-engineered humanized IgG1 anti-CD20 monoclonal antibody, with a Kd of ~100 pM. Ocaratuzumab exhibits more effective antibody-dependent cell-mediated cytotoxicity (ADCC). AME-133v (0.027-20 μg/mL) concentration-dependently inhibits the binding of biotinylated Rituximab to CD20 in SKW6.4 cells[1]. Kd: ~100 pM (CD20)[1] In Vitro AME-133v (0.027-20 μg/mL) concentration-dependently inhibits the binding of biotinylated Rituximab to CD20 in SKW6.4 cells[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Ocaratuzumab Related Antibodies Humanized Human IgG1 kappa Human IgG1 kappa, Isotype Control \| \| \| \| \| \| \| \| \| \| [1]. Forero-Torres A, et, al. Results of a phase 1 study of AME-133v (LY2469298), an Fc-engineered humanized monoclonal anti-CD20 antibody, in FcγRIIIa-genotyped patients with previously treated follicular lymphoma. Clin Cancer Res. 2012 Mar 1 18(5):1395-403. [Content Brief] [2]. Cheney CM, et, al. Ocaratuzumab, an Fc-engineered antibody demonstrates enhanced antibody-dependent cell-mediated cytotoxicity in chronic lymphocytic leukemia. MAbs. 2014 May-Jun 6(3):749-55. [Content Brief]
Supplier Website	https://www.medchemexpress.com/ocaratuzumab.html
Last Update	2025-05-21 16:50:25

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