Sumatriptan-d6 succinate MedChemExpress (MCE)

Product Name	Sumatriptan-d6 Succinate
Synonyms	Sumatriptan-d6 Succinate SUMATRIPTAN-D6 SUCCINATE Sumatriptan succinate salt [2H6]-Sumatriptan succinate 3-[2-(Dimethyl-d6-amino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide, Succinate, Imigran, Imitrex,
CAS	1215621-31-0
EINECS
Chemical Formula	C18H27N3O6S
Molecular Weight	413.49
inchi
Package	1 mg
Price	Email to quote
Descriptions	Sumatriptan-d6 succinate Sumatriptan-d6 succinate MedChemExpress (MCE) HY-B0121BS 1215621-31-0 GR 43175C-d6 99.63% -20°C, sealed storage, away from moisture In solvent : -80°C, 6 months Descriptions Sumatriptan-d6 succinate Sumatriptan-d6 succinate MedChemExpress (MCE) HY-B0121BS 1215621-31-0 GR 43175C-d6 99.63% -20°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Sumatriptan-d6 succinate is the deuterium labeled Sumatriptan succinate. Sumatriptan succinate is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for migraine headache research. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. \| \| \| \| \| \| \| \| \| \| [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb 53(2):211-216. [Content Brief] [2]. S J Peroutka, et al. Sumatriptan (GR 43175) interacts selectively with 5-HT1B and 5-HT1D binding sites. Eur J Pharmacol. 1989 Apr 12 163(1):133-6. [Content Brief] [3]. K L Dechant, et al. Sumatriptan. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the acute treatment of migraine and cluster headache. Drugs. 1992 May 43(5):776-98. [Content Brief]
Supplier Website	https://www.medchemexpress.com/sumatriptan-d6-succinate.html
Last Update	2025-05-21 16:50:25

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