Galanthamine-d6 MedChemExpress (MCE)

Product Name	Galanthamine-O-(methyl-d3)-N-(methyl-d3)
Synonyms	Lycoremine-d6 GalantaMin-d6 GalantaMina-d6 BRN 0093736-d6 Galantamine-d6 (-)-GalanthaMine-d6 Galanthamine-O-(methyl-d3)-N-(methyl-d3) Synonyms Lycoremine-d6 GalantaMin-d6 GalantaMina-d6 BRN 0093736-d6 Galantamine-d6 (-)-GalanthaMine-d6 Galanthamine-O-(methyl-d3)-N-(methyl-d3) (4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-3-(methoxy-d3)-11-(methyl-d3)-6H-benzofurol[3a,3,2,-ef][2]benzazepin-6-ol
CAS	1128109-00-1
EINECS
Chemical Formula	C17H21NO3
Molecular Weight	287.35354
inchi
Package	1 mg;5 mg
Price	Email to quote
Descriptions	Galanthamine-d6 Galanthamine-d6 MedChemExpress (MCE) HY-76299S 1128109-00-1 99.54% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions Galanthamine-d6 Galanthamine-d6 MedChemExpress (MCE) HY-76299S 1128109-00-1 99.54% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. Galanthamine-d6 (Galantamine-d6) is the deuterium labeled Galanthamine. Galanthamine is a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 500 nM[1][2]. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. \| \| \| \| \| \| \| \| \| \| [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 53(2):211-216. [Content Brief] [2]. Melanie-Jayne R. Howes, et al. Acetylcholinesterase inhibitors of natural origin. International Journal of Research in Pharmaceutical and Biomedical Sciences 3(SI 1):67-86. [3]. Kuryatov A, et al. Roles of accessory subunits in alpha4beta2() nicotinic receptors. Mol Pharmacol. 2008 Jul 74(1):132-43. [Content Brief]* [4]. Kita Y, et al. Galantamine increases hippocampal insulin-like growth factor 2 expression via α7 nicotinic acetylcholine receptors in mice. Psychopharmacology (Berl). 2013 Feb 225(3):543-51. [Content Brief]
Supplier Website	https://www.medchemexpress.com/galanthamine-d6.html
Last Update	2025-05-21 16:50:25

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