Norfloxacin-d8 MedChemExpress (MCE)

Product Name	Norfloxacin-d8
Synonyms	MK-366-d8;Barazan-d8;Baccidal-d8;Chibroxine-d8;Norfloxacin-d8;N-DeMethylpefloxacin-d8;N-DesMethylpefloxacin-d8;1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl-d8)-3-quinolinecarboxylic Acid
CAS	1216601-32-9
EINECS
Chemical Formula	C16H18FN3O3
Molecular Weight	319.34
inchi
Package	2.5 mg;2.5 mg
Price	Email to quote
Descriptions	Norfloxacin-d8 Norfloxacin-d8 MedChemExpress (MCE) HY-B0132S1 1216601-32-9 MK-0366-d8 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions Norfloxacin-d8 Norfloxacin-d8 MedChemExpress (MCE) HY-B0132S1 1216601-32-9 MK-0366-d8 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Norfloxacin-d8 is the deuterium labeled Norfloxacin. Norfloxacin (MK-0366) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. \| \| \| \| \| \| \| \| \| \| [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 53(2):211-216. [Content Brief] [2]. Nelson JM, et al. Fluoroquinolone-resistant Campylobacter species and the withdrawal of fluoroquinolones from use in poultry: a public health success story. Clin Infect Dis. 2007 Apr 1 44(7):977-80. Epub 2007 Feb 14. [Content Brief] [3]. Pade?skaia EN. Norfloxacin: more than 20 years of clinical use, the results and place among fluoroquinolones in modern chemotherapy for infections. Antibiot Khimioter. 2003 48(9):28-36. [Content Brief] [4]. Rafalsky V, et al. Quinolones for uncomplicated acute cystitis in women. Cochrane Database Syst Rev. 2006 Jul 19 (3):CD003597. [Content Brief]
Supplier Website	https://www.medchemexpress.com/norfloxacin-d8.html
Last Update	2025-05-21 16:50:25

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