Piperonyl butoxide-d9 MedChemExpress (MCE)

Product Name	5-[2-[2-(1,1,2,2,3,3,4,4,4-nonadeuteriobutoxy)ethoxy]ethoxymethyl]-6-propyl-1,3-benzodioxole
Synonyms	[2H9]-Piperonyl Butoxide;Piperonylbutoxide-(butyl-d9);5-[2-[2-(1,1,2,2,3,3,4,4,4-nonadeuteriobutoxy)ethoxy]ethoxymethyl]-6-propyl-1,3-benzodioxole
CAS	1329834-53-8
EINECS
Chemical Formula	C19H21D9O5
Molecular Weight	347.493956002
inchi
Package	1 mg;10 mg
Price	Email to quote
Descriptions	Piperonyl butoxide-d9 Piperonyl butoxide-d9 MedChemExpress (MCE) HY-B1198S 1329834-53-8 ENT-14250-d9 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions Piperonyl butoxide-d9 Piperonyl butoxide-d9 MedChemExpress (MCE) HY-B1198S 1329834-53-8 ENT-14250-d9 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Piperonyl butoxide-d9 is the deuterium labeled Piperonyl butoxide.Piperonyl butoxide (ENT-14250) is a pesticide synergist and food additive. Piperonyl butoxide has adverse effects on reproduction, development and behavior in mice. Piperonyl butoxide can activate c-Jun and ATF-2 in mouse hepatocytes. Piperonyl butoxide is a liver cancer carcinogen in rats and mice. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. \| \| \| \| \| \| \| \| \| \| [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 53(2):211-216. [Content Brief] [2]. Muguruma M, et al. Piperonyl butoxide activates c-Jun and ATF-2 in the hepatocytes of mice. Arch Toxicol. 2008 Oct 82(10):749-53. [Content Brief] [3]. Tanaka T, et al. Effects of piperonyl butoxide on exploratory behaviour in female mice. Toxicol Ind Health. 2019 Apr 35(4):314-323. [Content Brief] [4]. Takahashi O, et al. Chronic toxicity studies of piperonyl butoxide in CD-1 mice: induction of hepatocellular carcinoma. Toxicology. 1997 Dec 26 124(2):95-103. [Content Brief]
Supplier Website	https://www.medchemexpress.com/piperonyl-butoxide-d9.html
Last Update	2025-05-21 16:50:25

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