L-Cycloserine MedChemExpress (MCE)

Product Name	Levcycloserine
Synonyms	102.09 cycloserinr L-cycloserine Levcycloserine Cyclo-L-serine Levocycloserine (S)-Cycloserine Synonyms 102.09 cycloserinr L-cycloserine Levcycloserine Cyclo-L-serine Levocycloserine (S)-Cycloserine (S)-(-)-Cycloserine Cycloserine Impurity 4 (S)-4-Aminoisoxazolidin-3-one (4S)-3-oxoisoxazolidin-4-aminium (4S)-4-amino-1,2-oxazolidin-3-one Cycloserine Impurity 4 (L-Cycloserine) L-Cycloserine,(S)-4-Amino-3-isoxazolidone
CAS	339-72-0
EINECS	206-427-0
Chemical Formula	C3H6N2O2
Molecular Weight	102.09
inchi	InChI=1/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/p+1/t2-/m0/s1
Package	10 mM * 1 mL;5 mg;10 mg;50 mg;100 mg
Price	Email to quote
Descriptions	L-Cycloserine L-Cycloserine MedChemExpress (MCE) HY-B1122 339-72-0 (S)-Cycloserine Descriptions L-Cycloserine L-Cycloserine MedChemExpress (MCE) HY-B1122 339-72-0 (S)-Cycloserine (S)-4-Amino-3-isoxazolidone 99.44% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. L-Cycloserine ((S)-4-Amino-3-isoxazolidone) is an oral inhibitor of the enzyme gamma-aminobutyric acid (GABA) transaminase (GABA-t) and branched-chain transaminases in Mycobacterium tuberculosis. L-Cycloserine has anticonvulsant properties and inhibits the synthesis of neurotensin in mouse brains. L-Cycloserine inhibits the growth of M. tuberculosis, with an MIC of 0.3 μg/mL[1]. L-Cycloserine (25-50 mg/kg, intraperitoneal injection, single dose) has anticonvulsant effects in mice[2]. L-Cycloserine (30-100 mg/kg, orally or via intraperitoneal injection, twice daily for 5 days) enhances the inhibitory effect on GABA-T activity in mice and boosts its anticonvulsant effects[3]. L-Cycloserine (100-150 mg/kg, subcutaneous or intraperitoneal injection, once daily for 1 week) can reduce the brain content of gangliosides by 28% when injected subcutaneously, with no effect on the content of neurogangliosides intraperitoneal injection leads to decreased levels of gangliosides and cerebrosides[4]. L-Cycloserine (100 mg/kg, subcutaneous or intraperitoneal injection, single dose) affects the level of inhibition of 3-keto-dihydrosphingosine synthase depending on the method of injection[4]. \| \| \| \| \| \| \| \| \| \| [1]. Tathyana Mar Amorim Franco, et al. Mechanism-Based Inhibition of the Mycobacterium tuberculosis Branched-Chain Aminotransferase by d- and l-Cycloserine. ACS Chem Biol. 2017 May 19 12(5):1235-1244. [Content Brief] [2]. S H Chung, et al. L-cycloserine: a potent anticonvulsant. Epilepsia. 1984 Jun 25(3):353-62. [Content Brief] [3]. P Polc, et al. L-cycloserine: behavioural and biochemical effects after single and repeated administration to mice, rats and cats. Neuropharmacology. 1986 Apr 25(4):411-8. [Content Brief] [4]. K S Sundaram, et al. Inhibition of cerebroside synthesis in the brains of mice treated with L-cycloserine. J Lipid Res. 1985 Apr 26(4):473-7. [Content Brief]
Supplier Website	https://www.medchemexpress.com/L-Cycloserine.html
Last Update	2025-05-21 16:50:25

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