L-Palmitoylcarnitine MedChemExpress (MCE)

Product Name	Palmitoyl-L-carnitine
Synonyms	C02990 Palmitylcarnitine Palmitoyl-L-carnitine Palmitoyl L-carnitine Hexadecanoylcarnitine O-palmitoyl-L-carnitine (-)-[(R)-3-Carboxylato-2-(palmitoyloxy)propyl]trimethylaminium Synonyms C02990 Palmitylcarnitine Palmitoyl-L-carnitine Palmitoyl L-carnitine Hexadecanoylcarnitine O-palmitoyl-L-carnitine (-)-[(R)-3-Carboxylato-2-(palmitoyloxy)propyl]trimethylaminium (2R)-3-Carboxylato-N,N,N-trimethyl-2-[(1-oxohexadecyl)oxy]-1-propanaminium 1-PropanaMiniuM, 3-carboxy-N,N,N-triMethyl-2-[(1-oxohexadecyl)oxy]-, inner salt, (2R)-
CAS	2364-67-2
EINECS
Chemical Formula	C23H45NO4
Molecular Weight	399.61
inchi
Package	1 mg;5 mg
Price	Email to quote
Descriptions	L-Palmitoylcarnitine L-Palmitoylcarnitine MedChemExpress (MCE) HY-113147 2364-67-2 99.88% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions L-Palmitoylcarnitine L-Palmitoylcarnitine MedChemExpress (MCE) HY-113147 2364-67-2 99.88% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. L-Palmitoylcarnitine, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2. L-Palmitoylcarnitine (1 µM) inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2. L-Palmitoylcarnitine simultaneously enhances the ATP sensitivity of the channel (IC50 fell from 62 to 30 µM)[1]. Modulation of the membrane lipid environment caused by L-Palmitoylcarnitine alters the KATP channel function mainly through the interaction with endogenous PI cascade, especially PIP2[1]. Kir6.2 Human Endogenous Metabolite \| \| \| \| \| \| \| \| \| \| [1]. Haruna T, et al. Alteration of the membrane lipid environment by L-palmitoylcarnitine modulates K(ATP) channels in guinea-pig ventricular myocytes. Pflugers Arch. 2000 441(2-3):200-207. [Content Brief]
Supplier Website	https://www.medchemexpress.com/L-Palmitoylcarnitine.html
Last Update	2025-05-21 16:50:25

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