EIF2α activator 2 MedChemExpress (MCE)

Product Name	Urea, N-[trans-4-[4-(trifluoromethyl)phenoxy]cyclohexyl]-N'-[3-(trifluoromethyl)phenyl]-
Synonyms	Urea, N-[trans-4-[4-(trifluoromethyl)phenoxy]cyclohexyl]-N'-[3-(trifluoromethyl)phenyl]-
CAS	1501618-04-7
EINECS
Chemical Formula	C21H20F6N2O2
Molecular Weight	446.39
inchi
Package	10 mM * 1 mL;1 mg;5 mg;10 mg;25 mg
Price	Email to quote
Descriptions	EIF2α activator 2 EIF2α activator 2 MedChemExpress (MCE) HY-147832 1501618-04-7 99.88% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions EIF2α activator 2 EIF2α activator 2 MedChemExpress (MCE) HY-147832 1501618-04-7 99.88% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. EIF2α activator 2 (Compound 1) is an activator of eukaryotic initiation factor 2 alpha (eIF2α) phosphorylation. EIF2α activator 2 exhibits high potency in SRB cell proliferation assays (IC50=0.46 μM). EIF2α activator 2 exhibits antiproliferative activity againist K562 and PBMC cells with IC50s of 4.79 and 10.52 μM, respectively. \| \| \| \| \| \| \| \| \| \| [1]. Jinsook Kwak, et al. A bioisosteric approach to the discovery of novel N-aryl-N'-[4-(aryloxy)cyclohexyl]squaramide-based activators of eukaryotic initiation factor 2 alpha (eIF2α) phosphorylation. Eur J Med Chem. 2022 May 29 239:114501. [Content Brief]
Supplier Website	https://www.medchemexpress.com/eif2α-activator-2.html
Last Update	2025-05-21 16:50:25

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