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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product Name5-(1-Methyl-1H-pyrazol-4-yl)-4-(4-morpholinyl)-7H-Pyrrolo[2,3-d]pyrimidine
SynonymsCS-2879;PF06454589;PF-06454589;PF-06454589 ;PF 06454589 ;5-(1-Methyl-1H-pyrazol-4-yl)-4-(4-morpholinyl)-7H-Pyrrolo[2,3-d]pyrimidine
CAS1527473-30-8
EINECS
Chemical FormulaC14H16N6O
Molecular Weight284.32
inchi
Package10 mM * 1 mL;5 mg;10 mg;25 mg;50 mg;100 mg
PriceEmail to quote
DescriptionsPF-06454589

PF-06454589

MedChemExpress (MCE)

HY-112855

1527473-30-8

99.91%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

PF-06454589

PF-06454589

MedChemExpress (MCE)

HY-112855

1527473-30-8

99.91%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

PF-06447475 is a highly potent, selective, brain penetrant LRRK2 kinase inhibitor with IC50 values of 3 nM and 11 nM for WT LRRK and G2019S LRRK2, respectively. PF-06447475 can be used for parkinson's disease (PD) research.

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[1]. Jaclyn L Henderson, et al. Discovery and preclinical profiling of 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor. J Med Chem. 2015 Ja [Content Brief]

Supplier Websitehttps://www.medchemexpress.com/pf-06454589.html
Last Update2025-05-21 16:50:25
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