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Supplier NameMedChemExpress (MCE)
Contactsales
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product NameBMS-566419
SynonymsBMS-566419
N-[1-[6-(4-Ethyl-1-piperazinyl)-3-pyridinyl]-1-methylethyl]-2-fluoro-9,10-dihydro-9-oxo-3-acridinecarboxamide
3-Acridinecarboxamide, N-[1-[6-(4-ethyl-1-piperazinyl)-3-pyridinyl]-1-methylethyl]-2-fluoro-9,10-dihydro-9-oxo-

Synonyms

BMS-566419
N-[1-[6-(4-Ethyl-1-piperazinyl)-3-pyridinyl]-1-methylethyl]-2-fluoro-9,10-dihydro-9-oxo-3-acridinecarboxamide
3-Acridinecarboxamide, N-[1-[6-(4-ethyl-1-piperazinyl)-3-pyridinyl]-1-methylethyl]-2-fluoro-9,10-dihydro-9-oxo-
Unii-9688E11ZQ0
CAS566161-24-8
EINECS
Chemical FormulaC28H30FN5O2
Molecular Weight487.57
inchi
Package1 mg;5 mg;10 mg
PriceEmail to quote
DescriptionsBMS-566419

BMS-566419

MedChemExpress (MCE)

HY-110217

566161-24-8

99.68%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

BMS-566419

BMS-566419

MedChemExpress (MCE)

HY-110217

566161-24-8

99.68%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

BMS-566419 is an acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase (IMPDH). Inosine monophosphate dehydrogenase (IMPDH) is a key enzyme in the de novo synthesis of guanosine nucleotides. BMS-566419 has clinical utility for the research of transplant rejection.

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[1]. Watterson SH, et al. Acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase: discovery and SAR leading to the identification of N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419). J Med Chem. 2007
50(15):3730-3742.
[Content Brief]

Supplier Websitehttps://www.medchemexpress.com/bms-566419.html
Last Update2025-05-21 16:50:25
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