Lenalidomide-4-aminomethyl MedChemExpress (MCE)

Product Name	Lenalidomide-4-aminomethyl hydrochloride
Synonyms	Lenalidomide-4-aminomethyl hydrochloride;3-(4-(aminomethyl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione HCL;3-(4-(aminomethyl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione hydrochloride
CAS	444289-05-8
EINECS
Chemical Formula	C14H16ClN3O3
Molecular Weight	309.75
inchi
Package	5 mg;10 mg;25 mg;50 mg;100 mg
Price	Email to quote
Descriptions	Lenalidomide-4-aminomethyl hydrochloride Lenalidomide-4-aminomethyl hydrochloride MedChemExpress (MCE) HY-138882A 444289-05-8 90.88% -20°C, sealed storage, away from moisture In solvent : -80°C, 6 months Descriptions Lenalidomide-4-aminomethyl hydrochloride Lenalidomide-4-aminomethyl hydrochloride MedChemExpress (MCE) HY-138882A 444289-05-8 90.88% -20°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Lenalidomide-4-aminomethyl hydrochloride is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-4-aminomethyl hydrochloride can be connected to the ligand for protein by a linker to form PROTAC PROTACs contain two different ligands connected by a linker one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. Cereblon \| \| \| \| \| \| \| \| \| \| [1]. Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019 17:160-176. Published 2019 Jan 25. [Content Brief] [2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020 27(8):998-985. [Content Brief]
Supplier Website	https://www.medchemexpress.com/lenalidomide-4-aminomethyl-hydrochloride.html
Last Update	2025-05-21 16:50:25

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