Pomalidomide 4'-PEG3-azide MedChemExpress (MCE)

Product Name	Pomalidomide 4'-PEG3-azide
Synonyms	IUN-36463;Pomalidomide 4'-PEG3-azide;Pomalidomide-NH-PEG3-azide;4-((2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
CAS	2271036-46-3
EINECS
Chemical Formula	C21H26N6O7
Molecular Weight	474.47
inchi
Package	1 mg;5 mg;10 mg;25 mg;50 mg;100 mg
Price	Email to quote
Descriptions	Pomalidomide 4'-PEG3-azide Pomalidomide 4'-PEG3-azide MedChemExpress (MCE) HY-130652 2271036-46-3 96.06% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions Pomalidomide 4'-PEG3-azide Pomalidomide 4'-PEG3-azide MedChemExpress (MCE) HY-130652 2271036-46-3 96.06% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. Pomalidomide 4'-PEG3-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and a linker. Pomalidomide 4'-PEG3-azide can be used for the synthesis of iRucaparib-TP3 (Compound 3). iRucaparib-TP3 is a highly efficient PARP1?degrader based on Rucaparib by using the PROTAC approach. Pomalidomide 4'-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Cereblon \| \| \| \| \| \| \| \| \| \| [1]. Shuai Wang, et al. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation. Nat Chem Biol. 2019 Dec 15(12):1223-1231. [Content Brief]
Supplier Website	https://www.medchemexpress.com/pomalidomide-4-peg3-azide.html
Last Update	2025-05-21 16:50:25

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