endo-BCN-PEG2-NH2 MedChemExpress (MCE)

Product Name	N-[(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl]-1,8-diamino-3,6-dioxaoctane
Synonyms	N-[(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl]-1,8-diamino-3,6-dioxaoctane
CAS	1263166-93-3
EINECS
Chemical Formula	C17H28N2O4
Molecular Weight	324.42
inchi
Package	5 mg;10 mg;25 mg;50 mg
Price	Email to quote
Descriptions	endo-BCN-PEG2-NH2 endo-BCN-PEG2-NH2 MedChemExpress (MCE) HY-W072752 1263166-93-3 97.0% Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions endo-BCN-PEG2-NH2 endo-BCN-PEG2-NH2 MedChemExpress (MCE) HY-W072752 1263166-93-3 97.0% Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. endo-BCN-PEG2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. endo-BCN-PEG2-NH2 contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. PROTACs contain two different ligands connected by a linker one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. PEGs \| \| \| \| \| \| \| \| \| \| [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct 36:553-562 [Content Brief]
Supplier Website	https://www.medchemexpress.com/endo-bcn-peg2-nh2.html
Last Update	2025-05-21 16:50:25

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