DBCO-PEG3-amine MedChemExpress (MCE)

Product Name	DBCO-PEG3-amine
Synonyms	DBCO-PEG3-amine;DBCO-PEG3-amine,DBCO-PEG3-NH2;Dibenz[b,f]azocine-5(6H)-butanamide, N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-11,12-didehydro-γ-oxo-
CAS	2093409-57-3
EINECS
Chemical Formula	C27H33N3O5
Molecular Weight	479.58
inchi
Package	50 mg
Price	Email to quote
Descriptions	DBCO-PEG3-amine DBCO-PEG3-amine MedChemExpress (MCE) HY-134714 2093409-57-3 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions DBCO-PEG3-amine DBCO-PEG3-amine MedChemExpress (MCE) HY-134714 2093409-57-3 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. DBCO-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DBCO-PEG3-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. PROTACs contain two different ligands connected by a linker one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. PEGs \| \| \| \| \| \| \| \| \| \| [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct 36:553-562 [Content Brief]
Supplier Website	https://www.medchemexpress.com/dbco-peg3-amine.html
Last Update	2025-05-21 16:50:25

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