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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product Name(2S)-N-[4-[[3-Cyano-1-[(3,5-dimethyl-4-isoxazolyl)methyl]-1H-indol-5-yl]oxy]phenyl]-2-pyrrolidinecarboxamide
SynonymsAZ PFKFB3 67;(2S)-N-[4-[[3-Cyano-1-[(3,5-dimethyl-4-isoxazolyl)methyl]-1H-indol-5-yl]oxy]phenyl]-2-pyrrolidinecarboxamide
CAS1704741-11-6
EINECS
Chemical FormulaC26H25N5O3
Molecular Weight455.5084
inchi
Package10 mM * 1 mL;1 mg;5 mg;10 mg;25 mg
PriceEmail to quote
DescriptionsAZ-PFKFB3-67

AZ-PFKFB3-67

MedChemExpress (MCE)

HY-101972

1704741-11-6

97.20%

Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

AZ-PFKFB3-67

AZ-PFKFB3-67

MedChemExpress (MCE)

HY-101972

1704741-11-6

97.20%

Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

AZ-PFKFB3-67 is potent and selective metabolic kinase PFKFB3 inhibitor, with IC50s of 11, 159 and 1130 nM for PFKFB3, PFKFB2 and PFKFB1 respectively.

IC50: 11 nM (PFKFB3), 159 nM (PFKFB2), 1130 nM (PFKFB1)[1] Cellular Effect Cell Line Type Value Description References

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[1]. Boyd S, et al. Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3. J Med Chem. 2015
58(8):3611-3625. [Content Brief]

Supplier Websitehttps://www.medchemexpress.com/az-pfkfb3-67.html
Last Update2025-05-21 16:50:25
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