4-CMTB MedChemExpress (MCE)

Product Name	4-Chloro-α-(1-methylethyl)-N-2-thiazolyl-benzeneacetamide
Synonyms	4-CMTB 2-(4-Chloro-phenyl)-3-methyl-N-thiazol-2-yl-butyramide 2-(4-Chlorophenyl)-3-methyl-N-(thiazol-2-yl)butanamide 4-CHLORO-Α-(1-METHYLETHYL)-N-2-THIAZOLYL-BENZENEACETAMIDE 4-Chloro-α-(1-methylethyl)-N-2-thiazolyl-benzeneacetamide Synonyms 4-CMTB 2-(4-Chloro-phenyl)-3-methyl-N-thiazol-2-yl-butyramide 2-(4-Chlorophenyl)-3-methyl-N-(thiazol-2-yl)butanamide 4-CHLORO-Α-(1-METHYLETHYL)-N-2-THIAZOLYL-BENZENEACETAMIDE 4-Chloro-α-(1-methylethyl)-N-2-thiazolyl-benzeneacetamide Benzeneacetamide, 4-chloro-α-(1-methylethyl)-N-2-thiazolyl-
CAS	300851-67-6
EINECS
Chemical Formula	C14H15ClN2OS
Molecular Weight	294.8
inchi
Package	1 mg;5 mg;10 mg;25 mg;50 mg
Price	Email to quote
Descriptions	4-CMTB 4-CMTB MedChemExpress (MCE) HY-P1125 300851-67-6 99.64% 4°C, protect from light In solvent : -80°C, 6 months Descriptions 4-CMTB 4-CMTB MedChemExpress (MCE) HY-P1125 300851-67-6 99.64% 4°C, protect from light In solvent : -80°C, 6 months -20°C, 1 month (protect from light) Room temperature in continental US may vary elsewhere. 4-CMTB is a selective free fatty acid receptor 2 (FFA2/GPR43) agonist and a positive allosteric modulator (pEC50=6.38). 4-CMTB is both a direct agonist and a positive allosteric modulator of the action of short-chain free fatty acids. 4-CMTB modulates the activity of short-chain fatty acids at FFA2 via the FFA2 second extracellular loop (ECL2)[1][2]. \| \| \| \| \| \| \| \| \| \| [1]. Smith NJ, et al. Extracellular loop 2 of the free fatty acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator. Mol Pharmacol. 2011 80(1):163-173. [Content Brief] [2]. Milligan G, Stoddart LA, Smith NJ. Agonism and allosterism: the pharmacology of the free fatty acid receptors FFA2 and FFA3. Br J Pharmacol. 2009 158(1):146-153. [Content Brief]
Supplier Website	https://www.medchemexpress.com/4-cmtb.html
Last Update	2025-05-21 16:50:25

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