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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product Name(3-Chloro-4-methylphenyl)[4-(4-nitrophenyl)-1-piperazinyl]-methanone
SynonymsFilastatin;(3-Chloro-4-methylphenyl)[4-(4-nitrophenyl)-1-piperazinyl]-methanone
CAS431996-53-1
EINECS
Chemical FormulaC18H18ClN3O3
Molecular Weight359.80682
inchi
Package1 mg;5 mg;10 mg;25 mg;50 mg;100 mg
PriceEmail to quote
DescriptionsFilastatin

Filastatin

MedChemExpress (MCE)

HY-124701

431996-53-1

99.27%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

Filastatin

Filastatin

MedChemExpress (MCE)

HY-124701

431996-53-1

99.27%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

Filastatin is a long-lasting inhibitor of Candida albicans filamentation. Filastatin inhibits adhesion by multiple pathogenic Candida species with an IC50 of ~3 μM in the GFP-based adhesion assay. Filastatin inhibits fungal adhesion to polystyrene and human cells, the yeast-to-hyphal morphological transition, induction of the hyphal-specific HWP1 promoter. Filastatin has potent antifungal effect.

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[1]. Ahmed Fazly, et al. Chemical screening identifies filastatin, a small molecule inhibitor of Candida albicans adhesion, morphogenesis, and pathogenesis. Proc Natl Acad Sci U S A. 2013 Aug 13
110(33):13594-9. [Content Brief]

Supplier Websitehttps://www.medchemexpress.com/filastatin.html
Last Update2025-05-21 16:50:25
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