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  6. Mal-Ph-CONH-PEG4-​NHS ester

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Supplier NameMedChemExpress (MCE)
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Emailsales@medchemexpress.com; tech@medchemexpress.com
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Product Name2,5-dioxopyrrolidin-1-yl 1-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl)-1-oxo-5,8,11,14-tetraoxa-2-azaheptadecan-17-oate
SynonymsMal-Ph-CONH-PEG4-?NHS ester
2,5-dioxopyrrolidin-1-yl 1-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl)-1-oxo-5,8,11,14-tetraoxa-2-azaheptadecan-17-oate
Propanoic acid, 3-[[13-[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)phenyl]-13-oxo-3,6,9-trioxa-12-azatridec-1-yl]oxy]-, 2,5-dioxo-1-pyrrolidinyl ester
CAS1263044-88-7
EINECS
Chemical FormulaC26H31N3O11
Molecular Weight561.54
inchi
Package50 mg;100 mg;250 mg;500 mg
PriceEmail to quote
DescriptionsMal-Ph-CONH-PEG4-​NHS ester

Mal-Ph-CONH-PEG4-​NHS ester

MedChemExpress (MCE)

HY-133545

1263044-88-7

97.0%

Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

Mal-Ph-CONH-PEG4-​NHS ester

Mal-Ph-CONH-PEG4-​NHS ester

MedChemExpress (MCE)

HY-133545

1263044-88-7

97.0%

Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

Mal-Ph-CONH-PEG4- NHS ester is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Non-cleavable Linker

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[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May
16(5):315-337.
[Content Brief]

Supplier Websitehttps://www.medchemexpress.com/mal-ph-conh-peg4-nhs-ester.html
Last Update2025-05-21 16:50:25
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