EMI48 MedChemExpress (MCE)

Product Name	7-(diethylamino)-3-(5-methylbenzoxazol-2-yl)-2-benzopyrone
Synonyms	EMI48 3-(5-Methylbenzoxazole-2-yl)-7-(diethylamino)coumarin 7-(diethylamino)-3-(5-methylbenzoxazol-2-yl)-2-benzopyrone 7-Diethylamino-3-(5-methylbenzoxazol-2-yl)-2H-1-benzopyran-2-one 3-(5-Methylbenzoxazole-2-yl)-7-(diethylamino)-2H-1-benzopyran-2-one Synonyms EMI48 3-(5-Methylbenzoxazole-2-yl)-7-(diethylamino)coumarin 7-(diethylamino)-3-(5-methylbenzoxazol-2-yl)-2-benzopyrone 7-Diethylamino-3-(5-methylbenzoxazol-2-yl)-2H-1-benzopyran-2-one 3-(5-Methylbenzoxazole-2-yl)-7-(diethylamino)-2H-1-benzopyran-2-one 2H-1-Benzopyran-2-one, 7-(diethylamino)-3-(5-methyl-2-benzoxazolyl)-
CAS	34564-13-1
EINECS	252-093-4
Chemical Formula	C21H20N2O3
Molecular Weight	348.4
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Package	10 mM * 1 mL;1 mg;5 mg;10 mg
Price	Email to quote
Descriptions	EMI48 EMI48 MedChemExpress (MCE) HY-131066 34564-13-1 99.02% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions EMI48 EMI48 MedChemExpress (MCE) HY-131066 34564-13-1 99.02% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. EMI48, the derivative of EMI1, displays greater potency toward mutant EGFR than EMI1. EMI48 inhibits EGFR triple mutants. EMI48 inhibits EGFR ex19del/T790M/C797S and EGFR L858R/T790M/C797S. EMI48 can be used in the research of mutant EGFR-associated, drug-resistant non-small-cell lung cancer (NSCLC)[1]. EGFRL858R/T790M/C797S EGFRdel19 T790M C797S \| \| \| \| \| \| \| \| \| \| [1]. Punit Saraon , et al. A Drug Discovery Platform to Identify Compounds That Inhibit EGFR Triple Mutants.Nat Chem Biol. 2020 May 16(5):577-586. [Content Brief]
Supplier Website	https://www.medchemexpress.com/emi48.html
Last Update	2025-05-21 16:50:25

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