Alkyne-PEG4-maleimide MedChemExpress (MCE)

Product Name	3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(3,6,9,12-tetraoxapentadec-14-yn-1-yl)propanamide
Synonyms	Alkyne-PEG4-NH-Mal PROPARGYL-PEG4-AMIDO-MAL Propargyl-PEG4-Maleimide Propargyl-PEG4-amido-Maleimide Alkyne-PEG4-Maleimide,Propargyl-PEG4-Maleimide 1H-Pyrrole-1-propanamide, 2,5-dihydro-2,5-dioxo-N-3,6,9,12-tetraoxapentadec-14-yn-1-yl- Synonyms Alkyne-PEG4-NH-Mal PROPARGYL-PEG4-AMIDO-MAL Propargyl-PEG4-Maleimide Propargyl-PEG4-amido-Maleimide Alkyne-PEG4-Maleimide,Propargyl-PEG4-Maleimide 1H-Pyrrole-1-propanamide, 2,5-dihydro-2,5-dioxo-N-3,6,9,12-tetraoxapentadec-14-yn-1-yl- 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(3,6,9,12-tetraoxapentadec-14-yn-1-yl)propanamide
CAS	1609651-90-2
EINECS
Chemical Formula	C18H26N2O7
Molecular Weight	382.41
inchi
Package	100 mg;250 mg;1 g
Price	Email to quote
Descriptions	Alkyne-PEG4-maleimide Alkyne-PEG4-maleimide MedChemExpress (MCE) HY-133399 1609651-90-2 98.0% Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions Alkyne-PEG4-maleimide Alkyne-PEG4-maleimide MedChemExpress (MCE) HY-133399 1609651-90-2 98.0% Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. Alkyne-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Alkyne-PEG4-maleimide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs contain two different ligands connected by a linker one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. PEGs \| \| \| \| \| \| \| \| \| \| [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct 36:553-562 [Content Brief]
Supplier Website	https://www.medchemexpress.com/alkyne-peg4-maleimide.html
Last Update	2025-04-01 14:45:47

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